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SCThrive for Sickle Cell Disease Self-Management

This study is testing a program called SCThrive to help teenagers and young adults (ages 13-21) with sickle cell disease (SCD) better manage their health. SCThrive is an 8-week online group program that uses a mobile app. The study wants to see if SCThrive improves how well you manage your SCD, your daily life, and if it can reduce emergency room visits. You can join if you are 13-21 years old, have SCD, and are a patient at a participating clinic. The study is looking for 310 participants and is currently unclear about its recruitment status. Success would mean participants show better self-management and fewer emergency room visits after using SCThrive.

Study design
This is an interventional study planning to enroll 310 participants. It compares SCThrive, a behavioral intervention, with standard care plus educational text messages.
What's involved
Participants will complete surveys before, after, and 3 months following an 8-week virtual group intervention with a mobile app.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 3 to 4 months after the treatment ends.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06290401

A Socio-ecological Approach for Improving Self-management in Adolescents With SCD

Recruiting
NAAges 13–21InterventionalTreatment
Children's Hospital Medical Center, Cincinnati
~310 participants
Updated 2026-05-11 on ClinicalTrials.gov
What's tested:SCThriveSCHealthED

At a glance

Recruiting sites
1 of 4 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patient Activation
Measured over baseline, up to 4 weeks after treatment ends, 3 to 4 months after treatment ends

Conditions

Anemia, Sickle Cell

Explore related trials

Sickle Cell Disease

Where it's being run

4 sites across 4 states
Delaware1
Georgia1
Ohio1
Pennsylvania1

Study leadership

  • Lori E. Crosby, PsyD · PRINCIPAL_INVESTIGATOR · Children's Hospital Medical Center, Cincinnati

Who to contact

Ama Wilson, MPH
[email protected]
15136365380
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patient of a participating SCD Clinic
Confirmed diagnosis of SCD
13-21 years of age

Exclusion

Another chronic disease (which would complicate measurement of patient activation)
Non-English-speaking
Cognitive or psychiatric disorder that the physician or study therapists believe would impair study participation.

What this trial measures

  • Patient Activationbaseline, up to 4 weeks after treatment ends, 3 to 4 months after treatment ends

    Self-reported patient activation as measured by the Patient Activation Measure -13 (PAM-13), which is a 13 item measure on skills, knowledge, confidence and readiness for self-management developed by Hibbard et al., 2005. Items are rated on a 4-point Likert scale of 1 = "Disagree Strongly" to 3 = "Strongly Agree." Raw scores range from 13 to 52 and are converted to scores that range from 0 to 100. This score was then divided into four levels of activation, which reflect a developmental progression from being passive with regard to one's health to being proactive: Level 1 (score of 0.0 - 47.0), Level 2 (47.1 - 55.1), Level 3 (55.2 - 72.4), and Level 4 (72.5 - 100). Higher scores indicate more behavioral activation.