Manual Lymphatic Drainage Breast Massage After Breast Conserving Surgery

This study is looking at manual lymphatic drainage (MLD) breast massage for women who have had breast conserving surgery (lumpectomy) for localized breast cancer (cancer that has not spread) and are receiving radiation therapy. The goal is to see if MLD breast massage can help reduce side effects like swelling (lymphedema), pain, and improve quality of life. MLD is a gentle massage technique used to reduce swelling. The study will enroll 50 women aged 18 or older who are able to understand and sign consent forms in English or Spanish. The main thing being measured is how well participants follow the MLD breast massage schedule for up to one month after radiation ends. The study status is unclear.

Study design
This is an interventional study with an estimated enrollment of 50 participants. It is not specified if the study is randomized or blinded.
What's involved
You would receive MLD breast massage for 30-60 minutes twice a week during your radiation therapy and for one month afterward. You would also have follow-up visits at 2-4 weeks, 3, 6, and 12 months after radiation.
Compensation
Not stated in the trial record.
Follow-up
Participants are followed for up to 12 months after completing radiation therapy.

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NCT06297265

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery

Recruiting
NAAges 18+InterventionalSupportive care
University of Southern California
~50 participants
Updated 2026-06-05 on ClinicalTrials.gov
What's tested:Lymphedema ManagementQuestionnaire AdministrationAdjuvant breast radiation therapy

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Rate of compliance of MLD breast massage sessions
Measured over Up to 1 month after completion of radiation
Anatomic Stage 0 Breast Cancer AJCC v8
Anatomic Stage IA Breast Cancer AJCC v8
Localized Breast Carcinoma
1 sites across 1 states
California1
  • May L Tao, MD · PRINCIPAL_INVESTIGATOR · University of Southern California

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Eligibility criteria

Inclusion

Female with native breasts and localized breast cancer who are status post-lumpectomy surgery, will receive whole breast radiation therapy with/without nodal irradiation, with standard fractionation or moderate hypofractionation
Age \>= 18 years
Ability to understand and the willingness to sign a written informed consent in English or Spanish

Exclusion

Underlying diagnosis of chronic inflammatory illness or collagen vascular disorder, e.g. scleroderma, lupus, rheumatoid arthritis, fibromyalgia as these conditions may significantly affect the likelihood and magnitude of radiation related toxicity
Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, unstable cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements
Inability to provide written informed consent in English or Spanish
Patients receiving ultra-hypofractionation, and/or partial breast or chest wall radiation therapy are excluded
  • Rate of compliance of MLD breast massage sessionsUp to 1 month after completion of radiation

    The intervention compliance rate will be calculated as the percentage of completed treatment sessions over the total targeted treatment sessions.