Ondansetron for Preventing Itching During Cesarean Section
This study is looking at whether the timing of giving ondansetron, a common medication, can help prevent itching (pruritus) in women having a Cesarean section. Itching is a frequent side effect when opioids are used for pain relief during this surgery. Researchers want to see if giving ondansetron at a specific time can reduce how often and how severely this itching happens. You might be able to join if you are a woman between 18 and 50 years old, scheduled for an elective Cesarean section with spinal anesthesia, and are otherwise healthy. The study aims to understand if ondansetron can effectively reduce itching in the first 24 hours after surgery. The current status of this study is unclear.
- Study design
- This is a randomized, double-blinded study, meaning participants are assigned to groups by chance and neither you nor your doctors will know which treatment you are receiving. It plans to enroll 66 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be assessed for itching during the first hour after surgery and again over the first 24 hours post-operative period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean Section
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Pruritus parameters in Post anesthesia Care Unit (PACU)Assessment during 1st post-operative hour in PACU
Patient Assessment (patient questionnaire): Pruritus occurrence (Yes or no) and anatomical location of Pruritus of occurrence, Severity of Pruritus- Likert scale choices from (Not present, Mild, Moderate, Severe, Unbearable) severity
- Pruritus severity in Post anesthesia Care Unit (PACU)Assessment during 1st post-operative hour in PACU
Severity of Pruritus- Likert scale choices from (Not present, Mild, Moderate, Severe, Unbearable) severity
- Pruritus parameters PACUAssessment during 24 hours post-operative period
Patient Assessment (patient questionnaire): Pruritus occurrence (Yes or no) and anatomical location of pruritus location
- Pruritus severity PACUAssessment during 24 hours post-operative period
Patient Assessment (patient questionnaire): Pruritus Severity: Likert scale: choice of (Not present, Mild, Moderate, Severe, Unbearable)
- Rescue Pruritus Treatment medicationMeasured in the 24 hour period from initial study treatment (30 minute period before intrathecal morphine administration.
Patient Assessment questionnaire: If rescue Pruritus treatment was required (YES/NO) and if so specific medication type and dose amount of medication
- Nausea PACUAssessment every 15 minutes for 1 hour
Patient Assessment questionnaire: Severity of Nausea- Likert scale: choice of (Not present, Mild, Moderate, Severe, Unbearable)
- Nausea Post PACUour period after patients left PACU from initial study treatment (30 minute period before intrathecal morphine administration.
Patient Assessment questionnaire: Severity of Nausea- Likert scale: choice of (Not present, Mild, Moderate, Severe, Unbearable)