The BRAIN App for Dementia and Alzheimer's Disease

This study is testing a digital tool called The BRAIN App for people with dementia, including Alzheimer's disease and vascular dementia. The app uses artificial intelligence (AI) to create personalized activities based on each person's interests. Researchers want to see if using The BRAIN App can improve engagement and quality of life for people with dementia, their family members, and caregivers. To join, you must be 65 or older, have a diagnosis of dementia, and be able to speak conversational English. The study will measure engagement using specific scales at the beginning and after several weeks of using the app. The current recruitment status is unclear.

Study design
This study plans to enroll 120 participants with dementia. It uses a quasi-experimental design, comparing a group using The BRAIN App to a control group.
What's involved
If you are a person with dementia, you will participate in the study for 16 weeks. If you are a family member, you will help with the BRAIN intervention twice a month and give feedback. Staff members will take training, use the platform, and provide feedback.
Compensation
Not stated in the trial record.
Follow-up
Engagement will be measured at baseline (Weeks 1-4) and during the intervention period (Weeks 5-16).

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NCT06298474

The BRAIN App (Phase 2 SBIR)

Recruiting
NAAges 65+InterventionalTreatment
Hopeful Aging
~120 participants
Updated 2025-06-19 on ClinicalTrials.gov
What's tested:The BRAIN App

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Menorah Park Engagement Scale (MPES)
Measured over Baseline, that is, Weeks 1 - 4
+3 more outcomes measured
Dementia
Alzheimer Disease
Vascular Dementia
1 sites across 1 states
Massachusetts1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

65+ years old
Clinical diagnosis of dementia (any type)
Able to speak conversational English

Exclusion

Completely unable to communicate verbally
Serious visual or hearing impairments
Signs of rapid decline over the last three months (based upon staff report)
  • Menorah Park Engagement Scale (MPES)Baseline, that is, Weeks 1 - 4

    The Menorah Park Engagement Scale measures four types of engagement. Constructive Engagement, Passive Engagement, Other Engagement, and Non-Engagement. It also measures pleasure. Scores on each type of engagement item range from 0 to 2 with higher scores indicating a better outcome for Constructive Engagement, Passive Engagement, and Pleasure. Higher scores represent worse outcomes for Distracted and Non Engagement.

  • Menorah Park Engagement Scale (MPES)Intervention Period, that is, Weeks 5-16

    The Menorah Park Engagement Scale measures four types of engagement. Constructive Engagement, Passive Engagement, Other Engagement, and Non-Engagement. It also measures pleasure. Scores on each type of engagement item range from 0 to 2 with higher scores indicating a better outcome for Constructive Engagement, Passive Engagement, and Pleasure. Higher scores represent worse outcomes for Distracted and Non Engagement.

  • Engagement for Persons with Dementia Scale (EPWDS)Baseline, that is, Weeks 1 - 4

    This scale measures the engagement in 5 domains: affective, visual, verbal, behavioral and social. Scores range from zero (0) to 36 with higher scores indicating a better outcome.

  • Engagement for Persons with Dementia Scale (EPWDS)Baseline, that is, Weeks 5-16

    This scale measures the engagement in 5 domains: affective, visual, verbal, behavioral and social. Scores range from zero (0) to 36 with higher scores indicating a better outcome.