Endoscopic Sleeve Gastroplasty Techniques for Weight Loss

This study is comparing two different ways to perform Endoscopic Sleeve Gastroplasty (ESG) for weight loss in people with obesity. ESG is a procedure where sutures are placed inside the stomach to reduce its size and help with weight loss. Researchers want to see if placing sutures in just the lower part of the stomach (called "belt only") is as effective as placing them in both the lower and upper parts of the stomach ("belt and suspenders"). You might be able to join if you are 18-65 years old, have a BMI (Body Mass Index) of 30 or higher, and are able to give informed consent. The study will measure how much weight participants lose and any side effects over 6 and 12 months. This study is currently recruiting 10 participants.

Study design
This interventional study will compare two different endoscopic sleeve gastroplasty techniques in 10 participants.
What's involved
You would have your weight loss measured at the start of the study, and then again at 6 months and 12 months after the procedure. Adverse events will also be monitored at these time points.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months after the procedure to measure weight loss and adverse events.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06299644

Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss

Not Yet Recruiting
NAAges 18–65InterventionalTreatment
Brigham and Women's Hospital
~10 participants
Updated 2025-12-02 on ClinicalTrials.gov
What's tested:Endoscopic Sleeve Gastroplasty - Belt and SuspendersEndoscopic Sleeve Gastroplasty - Belt

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percent TWL (%TWL)
Measured over Baseline, 6 months, 12 months
+1 more outcome measured
Obesity
Obesity, Morbid
Metabolic Disease
Weight, Body
1 sites across 1 states
Massachusetts1
  • Christopher C Thompson, MD, MSc · PRINCIPAL_INVESTIGATOR · Brigham and Women's Hospital

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  • Percent TWL (%TWL)Baseline, 6 months, 12 months

    Change in the percent total weight loss from baseline at 6 and 12 months.

  • Adverse Events6 months, 12 months

    Presence of adverse events that develop post-procedure