Back to search results

CT Scan Study for Atrial Fibrillation Before Ablation

This study is looking at how a special type of CT scan, called 320-detector Computed Tomography, can help doctors understand Atrial Fibrillation (AF) better before an ablation procedure. The CT scan measures something called extracellular volume (ECV) in your heart, which can show signs of scarring. Researchers want to see if higher ECV levels are linked to AF coming back or needing to go to the hospital after ablation. You might be able to join if you are at least 21 years old, have symptomatic AF, and your doctor thinks you are a good candidate for AF ablation. The study is currently unclear on its recruitment status.

Study design
This is an interventional study planning to enroll 100 participants. It uses a diagnostic CT scan to assess heart changes.
What's involved
You will have an additional CT scan of your left ventricle during your pre-ablation CT. Your health will be monitored for up to 90 days after your ablation procedure.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 90 days after the procedure to check for AF recurrence or hospitalizations.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06308094

320-detector Computed Tomography to Assess Myocardial Extracellular Volume Fraction in Patients With Atrial Fibrillation Before AF Ablation.

Recruiting
NAAges 21+InterventionalDiagnostic
Johns Hopkins University
~100 participants
Updated 2026-04-13 on ClinicalTrials.gov
What's tested:CT

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Recurrence of Atrial Fibrillation
Measured over Post procedure up to 90 days
+1 more outcome measured

Conditions

Atrial Fibrillation

Explore related trials

Atrial Fibrillation

NCT06308094

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Johns Hopkins Hospital

    Baltimore, Marylandno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Konstantinos Aronis, MD, PhD · PRINCIPAL_INVESTIGATOR · Johns Hopkins School of Medicine

Who to contact

Konstantinos Aronis, MD PHD
[email protected]
2017169226
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Patients must be at least 21 years old at the time of enrollment.
Patients must be able to give informed consent.
Patients with symptomatic paroxysmal/persistent atrial fibrillation (AF).
Eligible patients must be determined to be suitable candidates for ablation to treat AF by their cardiologist and/or electrophysiologists regardless of this protocol.
Patients are scheduled to have a pre-procedure cardiac CT upon the discretion of their electrophysiologists

Exclusion

Known allergy to iodinated contrast media.
Elevated serum creatinine (\> 1.5mg/dl) OR calculated creatinine clearance of \< 60 ml/min (using the Cockcroft-Gault formula).
Patients with a positive urine or serum pregnancy test will be excluded from this study.
Patients with heart transplantation.
Patients with polymorphic ventricular tachycardia (VT) or presenting in electrical storm.
Presence of any other history or condition that the investigator feels would be problematic.
Patient with iodinated contrast administration for other reason 24 hours prior to investigational CT.
Patients who have a heart pacemaker, metallic foreign body (metal sliver) in their eye, or who have an aneurysm clip in their brain, mechanical heart valves and prosthetics that contain metal.
Patients with severe claustrophobia.

What this trial measures

  • Recurrence of Atrial FibrillationPost procedure up to 90 days

    Patients will undergo computed tomography (CT) imaging with a total of 4 CT image acquisition (2 clinical and 2 research) During the follow-up visit with the primary electrophysiologist within 90 days after the procedure, the patient will be assessed for recurrence of atrial fibrillation.

  • Occurrence of ER visits, hospitalizations for cardiovascular causesPost procedure up to 90 days

    Patients will be assessed for any emergency room visits, or hospitalizations for any cardiovascular causes.