Observational Study of Improved MRI Techniques for Prostate Neoplasm

This observational study is looking at ways to make magnetic resonance imaging (MRI) better for people with prostate neoplasm (abnormal growth of cells in the prostate). Researchers are testing new technical approaches to improve how MRI scans show blood vessels (angiography) and blood flow (perfusion), both with and without using a contrast dye. The goal is to see if these improvements can lead to clearer and more useful MRI images. You might be able to join if you are an adult. The study plans to enroll about 1000 participants. The main way they'll measure success is by looking at how well the improved MRI techniques perform at the start of the study, with a possible second scan later on.

Study design
This is an observational study, meaning researchers will observe participants without giving them a specific treatment. It aims to include about 1000 participants.
What's involved
You would undergo a non-contrast MRI scan and might have a second non-contrast MRI scan later. You may also be asked to provide blood samples.
Compensation
Not stated in the trial record.
Follow-up
Improved performance in contrast-enhanced MRI is measured at the beginning of the study, with a possible second scan at a later date.

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NCT06315595

Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI

Recruiting
Not specifiedAges 18+Observational
Mayo Clinic
~1,000 participants
Updated 2026-04-17 on ClinicalTrials.gov
What's tested:Non-Interventional Study

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Improved performance in contrast-enhanced magnetic resonance imaging (MRI) as used for angiography and perfusion
Measured over Baseline (at enrollment); possible second scan at a later date
Prostate Neoplasm
2 sites across 2 states
Arizona1
Minnesota1
  • Stephen J. Riederer, PhD · PRINCIPAL_INVESTIGATOR · Mayo Clinic in Rochester

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Eligibility criteria

Inclusion

Adults
  • Improved performance in contrast-enhanced magnetic resonance imaging (MRI) as used for angiography and perfusionBaseline (at enrollment); possible second scan at a later date

    Assessed by comparison of two images made from the raw data set but reconstructed using the standard vs. an alternative algorithm (to be determined during study). Data will be tabulated and analyzed statistically.