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Study on Effects of Hypoxic Breathwork

This study is looking at how different types of breathwork affect your brain and body. Researchers are testing three approaches: hypoxic breathwork with music and positive messages, hypoxic breathwork alone, and music and positive messages alone. Hypoxic breathwork involves rhythmic breathing followed by holding your breath. The study aims to see how these practices change brain activity (measured by EEG, which looks at electrical signals in your brain) and sleep patterns over one week. You might be able to join if you are between 18 and 45 years old, in good general health, and willing to follow the breathwork routine. The study is looking for 75 participants.

Study design
This interventional study plans to enroll 75 participants to compare three different behavioral interventions: hypoxic breathwork with music and messaging, hypoxic breathwork only, and music and messaging meditation.
What's involved
You would participate in a week of daily breathwork practice. High-density EEG recordings will be done at the beginning and end of this week, and blood, urine, saliva, stool samples, biometric data, and sleep EEG will also be collected.
Compensation
Not stated in the trial record.
Follow-up
Your brain activity and sleep will be monitored at Day 7 and Day 14 or 21, comparing changes from your baseline measurements.

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NCT06317259

Effects of Hypoxic Breathwork

Recruiting
NAAges 18–45InterventionalBasic science
University of California, San Diego
~75 participants
Updated 2026-08-04 on ClinicalTrials.gov
What's tested:Hypoxic breathwork plus music and messagingHypoxic breathwork onlyMusic and messaging meditation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
EEG power and/or connectivity differences between groups
Measured over Day 7 and Day 14 or 21 (beginning and end of daily practice week)
+1 more outcome measured

Conditions

Hypoxic Breathwork With Music and Affirmative Messaging
Hypoxic Breathwork Only
Music and Affirmative Messaging

Explore related trials

Healthy

Where it's being run

1 sites across 1 states
California1

Who to contact

Julie Onton, PhD
[email protected]
8583362704
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Persons, aged 18-45
Availability for the duration of the study
In good general health as revealed by self-report
Stated willingness and capability to adhere to the breathwork regimen
Agreement to adhere to Lifestyle Considerations (see section 5.3) throughout study duration
Provision of signed and dated informed consent form

What this trial measures

  • EEG power and/or connectivity differences between groupsDay 7 and Day 14 or 21 (beginning and end of daily practice week)

    EEG features will be extracted to show the brain responses to rhythmic breathing and hypoxic breath holds that will be compared with music and positive messaging meditation. These groups will also be compared with a breathwork only condition.

  • Group differences in sleep EEG power and/or stage changes from baseline to the intervention periodDays 7-14 or 21 (intervention) vs Days 1-7 (baseline)

    Sleep stages and power characteristics will be analyzed during the practice week as compared to the week prior during which they have no intervention. All three experimental groups will be compared.