Weight Loss and Exercise for Post-stroke Veterans

This study is looking at how a 15-week weight management program called FOCUS-15 Lifestyle Management Program, along with exercise training, can help Veterans who have had a stroke. Researchers believe that losing weight and exercising could improve physical and emotional well-being for these Veterans. You might be able to join if you are a Veteran between 40 and 80 years old, had a stroke at least 6 months ago, have a BMI (Body Mass Index) over 30 kg/m2, and have some weakness in your leg from the stroke. The main goal is to see if these interventions improve how far you can walk in 6 minutes after about 15 weeks. The current status of this study is unclear, and it plans to enroll 99 participants.

Study design
This is an interventional study, meaning participants will receive specific treatments. It plans to enroll 99 participants.
What's involved
You would participate in a 15-week weight management program and progressive exercise training. You would also need to complete an exercise tolerance test.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome is measured at approximately 15 weeks.

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NCT06322030

Weight Loss and ExeRcise for Post-stroke Veterans

Recruiting
NAAges 40–80InterventionalTreatment
VA Office of Research and Development
~99 participants
Updated 2026-05-15 on ClinicalTrials.gov
What's tested:FOCUS-15 Lifestyle Management ProgramExercise Training

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in distance walk in 6 minute Walk Test
Measured over approximately 15 weeks
Stroke
1 sites across 1 states
South Carolina1
  • Chris M Gregory, PhD · PRINCIPAL_INVESTIGATOR · Ralph H. Johnson VA Medical Center, Charleston, SC

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

A diagnosis of stroke at least 6 months prior
BMI \> 30 kg/m2
Residual paresis in the lower extremity (Fugl-Meyer LE motor score \<34)
Ability to follow instructions, complete training and testing and to communicate exertion, pain and distress
Provision of informed consent

Exclusion

Unable to ambulate at least 150 feet or experienced intermittent claudication while walking
Unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's
Dementia
Life expectancy \<1 yr
History of DVT or pulmonary embolism within 6 months
Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions
Severe hypertension with systolic \>200 mmHg and diastolic \>110 mmHg at rest
Current enrollment in a rehabilitation trial to enhance motor or psychosocial recovery
  • Change in distance walk in 6 minute Walk Testapproximately 15 weeks

    Distance walk in 6 minutes