Back to search results

Ommaya Reservoir Placement for Brain Tumor Biomarker Collection

This study is looking at how well an Ommaya reservoir can be used to collect samples from people with brain tumors. An Ommaya reservoir is a small device placed under your scalp during a biopsy (when a small piece of tissue is removed for examination). This device allows doctors to collect cerebrospinal fluid (CSF), the fluid surrounding your brain and spinal cord, without needing a spinal tap in the future. The goal is to see if collecting these CSF samples over time can help identify "biomarkers" (measurable indicators of disease) that could eventually help doctors understand tumor growth and how well treatments are working. You may be able to join if you have a brain tumor and are already scheduled for a biopsy at Mayo Clinic in Rochester, MN, and are willing to have the Ommaya sampled at least twice in the future. The main goal is to see if placing the Ommaya reservoir is practical.

Study design
This is an interventional study planning to enroll 30 participants. It is not specified if it is randomized or blinded.
What's involved
You would undergo Ommaya reservoir placement, a biopsy, and CSF sample collection. You would also have a CT scan and agree to have your Ommaya sampled on at least two future occasions.
Compensation
Not stated in the trial record.
Follow-up
The feasibility of Ommaya reservoir placement will be measured for up to 5 years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06322602

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

Recruiting
NAAges 18+InterventionalBasic science
Mayo Clinic
~30 participants
Updated 2026-08-05 on ClinicalTrials.gov
What's tested:Intracranial Catheter PlacementLumbar PunctureBiopsyBiospecimen CollectionComputed TomographyMagnetic Resonance Imaging

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility of Ommaya reservoir placement
Measured over Up to 5 years

Conditions

Brain Neoplasms

Explore related trials

Brain Neoplasm

Where it's being run

1 sites across 1 states
Minnesota1

Study leadership

  • Terry C. Burns, M.D., Ph.D. · PRINCIPAL_INVESTIGATOR · Mayo Clinic in Rochester

Who to contact

Clinical Trials Referral Office
[email protected]
855-776-0015
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Clinical and radiographic evidence suggesting a diagnosis of a brain tumor
Planned biopsy for suspected or previously diagnosed brain tumor as part of routine clinical care at Mayo Clinic (Rochester, Minnesota \[MN\])
Willingness of the patient to provide informed consent
Patient is willing to have their Ommaya sampled on at least 2 future occasions
Patients is willing to have CSF banked through the neuro-oncology biorepository (requires a separate signature)

Exclusion

Vulnerable populations including pregnant women, prisoners, and individuals \< 18 years old
Patients who are not appropriate candidates for biopsy due to current or past medical history or uncontrolled current illness
Prior history of any wound infection
Any patient who the surgeon feels is not an optimal candidate for Ommaya reservoir placement. Such reasons may include, but will not be limited to, surgical anatomy, clinical evidence of immunosuppression, and/or elevated risk of wound infection due to diabetes, smoking history, morbid obesity, or any other concerns

What this trial measures

  • Feasibility of Ommaya reservoir placementUp to 5 years

    Will be assessed based on the percent of patients for whom an Ommaya reservoir is successfully placed at the time of tissue biopsy without attributable complication.