NCT06324110

Evaluating the Impact of Centralized Interventions on Lung Cancer Screening Adherence in Community Settings, ACCELL Trial

Enrolling by Invitation
NAAges 18+InterventionalScreening
Fred Hutchinson Cancer Center
~6,772 participants
Updated 2026-05-18 on ClinicalTrials.gov
What's tested:Electronic Health Record ReviewInterviewPatient Navigation

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Adherence to appropriate follow-up
Measured over Up to 48 months
Lung Carcinoma
1 sites across 1 states
Washington1
  • Matthew Triplette · PRINCIPAL_INVESTIGATOR · Fred Hutch/University of Washington Cancer Consortium

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

AIM II: Age 50-80
AIM II: Current or former (within 15 years) smoker
AIM II: 20+ pack-years of cigarette use
AIM II: Undergone at least one lung cancer screening low-dose chest computed tomography (CT) at partnering sites within the study period
AIM III (PROVIDER INTERVIEWS): Age minimum of 18
AIM III (PROVIDER INTERVIEWS): Affiliation with Skagit Regional Health System, Confluence Health or Kadlec Regional Medical Center
AIM III (PROVIDER INTERVIEWS): Identifies as providing primary care or specialty care to LCS patients (medical doctor \[MD\], registered nurse \[RN\], physician assistant \[PA\], advanced registered nurse practitioner \[ARNP\])
AIM III (LCS PATIENT INTERVIEWS): Aged 50-80 years
AIM III (LCS PATIENT INTERVIEWS): Received lung cancer screening at Skagit Regional Health System, Confluence Health or Kadlec Regional Medical Center within the intervention period
AIM III (LCS PATIENT INTERVIEWS): Was eligible for LCS at time of performance by United States Preventative Services Taskforce (USPSTF) criteria
Age 50-80 at time of exam
At least 20 pack-year smoking history
Currently smoking or smoked within the last 15 years
AIM III (LCS-SPECIFIC CARE COORDINATORS): Age minimum of 18
AIM III (LCS-SPECIFIC CARE COORDINATORS): Affiliation with Skagit Regional Health System, Confluence Health or Kadlec Regional Medical Center
AIM III (LCS-SPECIFIC CARE COORDINATORS): Identifies as fulfilling a supportive role in the LCS care continuum as part of the centralizing intervention
AIM II: Request to not participate in the trial
AIM III (PROVIDER INTERVIEWS): Less than age 18
AIM III (PROVIDER INTERVIEWS): Do not have an affiliation with Skagit Regional Health System, Confluence Health or Kadlec Regional Medical Center
AIM III (PROVIDER INTERVIEWS): Does not identify as providing primary care or specialty care to LCS patients (MD, RN, PA, ARNP)
AIM III (LCS PATIENT INTERVIEWS): Less than age 50 or older than age 80
AIM III (LCS PATIENT INTERVIEWS): Did not receive lung cancer screening at Skagit Regional Health System, Confluence Health or Kadlec Regional Medical Center within the intervention period
AIM III (LCS PATIENT INTERVIEWS): Was not eligible for LCS at time of performance by USPSTF criteria
AIM III (LCS-SPECIFIC CARE COORDINATORS): Less than of 18
AIM III (LCS-SPECIFIC CARE COORDINATORS): Does not have an affiliation with Skagit Regional Health System, Confluence Health or Kadlec Regional Medical Center
  • Adherence to appropriate follow-upUp to 48 months

    The time and covariate adjusted difference in adherence to appropriate follow-up will be assessed between the pre- and post-intervention period, separately for negative and positive exams. Follow-up will be considered on-time if occurring by the recommended follow up window + 30 days. The impact of the interventions on follow-up will be measured a using generalized estimating equations (GEE)-based approach. The modeling will be done using logistic regression. The Bonferroni correction will be used to account for testing two intervention coefficients.