Suvorexant and Alcohol Use Disorder Study

This study is looking at how a medication called suvorexant affects people with Alcohol Use Disorder (AUD). Researchers want to see if suvorexant can reduce the desire for alcohol and other behaviors linked to drinking. You might be able to join if you are between 21 and 55 years old, can speak and read English, and have experienced binge drinking recently. You also need to meet the criteria for moderate or severe AUD. The study will measure how alcohol affects your body and how suvorexant might change that. This research aims to help us better understand AUD and find new ways to treat it. The current status of this study is unclear.

Study design
This interventional study plans to enroll 30 participants. It will compare the effects of alcohol, a placebo (an inactive substance), and two different doses of suvorexant.
What's involved
You would be admitted to an inpatient facility for approximately 3 weeks. During this time, the reinforcing effects of alcohol will be measured at 6 different times.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, "Reinforcing Effects of Alcohol," is measured over approximately a 3-week inpatient admission. It is not specified if there is follow-up after this period.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06326684

Suvorexant and Alcohol

Recruiting
EARLY_PHASE1Ages 21–55InterventionalBasic science
William Stoops
~30 participants
Updated 2026-06-08 on ClinicalTrials.gov
What's tested:AlcoholPlaceboSuvorexant

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Reinforcing Effects of Alcohol
Measured over 6 times over approximately 3 week inpatient admission.
Alcohol Use Disorder
1 sites across 1 states
Kentucky1
  • William W Stoops, PhD · PRINCIPAL_INVESTIGATOR · University of Kentucky

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  • Reinforcing Effects of Alcohol6 times over approximately 3 week inpatient admission.

    Number of Times Subjects Choose Alcohol (Maximum of 5 Choices) Over Money