Social Network Overdose Prevention and Education Intervention

This study is testing a social intervention called "Network overdose prevention" to see if it can help prevent drug overdoses. It aims to teach people who use opioids, and their non-using friends or family, how to respond to an overdose. You might be able to join if you are 18 or older, live in the Baltimore area, have used illicit opioids at least twice in the last two weeks, and are willing to teach others and recruit a non-using friend or family member to participate. The researchers will measure the number of drug overdoses and your drug use after three months to see if the intervention is successful. The current status of this study is unclear.

Study design
This interventional study plans to enroll 600 participants. It compares a "Network overdose prevention" intervention with standard health education.
What's involved
Participants in the intervention group will have three individual sessions, and their non-using network member will have one session. The control group will have one session.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for three months to measure drug overdoses and drug use.

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NCT06327061

Social Network Overdose Prevention and Education Intervention

Recruiting
NAAges 18+InterventionalPrevention
Johns Hopkins Bloomberg School of Public Health
~600 participants
Updated 2026-03-04 on ClinicalTrials.gov
What's tested:Network overdose preventionStandard of care health education

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of drug overdoses
Measured over 3-months
+1 more outcome measured
Drug Overdose
1 sites across 1 states
Maryland1
  • Carl Latkin, PhD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University

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Eligibility criteria

Inclusion

self-reported illicit opioid use at least 2 times in the past two weeks;
age 18 and older;
living in the Baltimore metropolitan region;
willing to engage in peer education; and
having and willing to recruit at least one non-using network member.
  • Number of drug overdoses3-months

    Number of drug overdoses in prior three months

  • Participant drug use3-months

    Proportion of times participants tested positive for drugs of fentanyl and xylazine using test strips in the prior 3 months.