NCT06328114
Accelerating TMS for Cervical Dystonia
Enrolling by Invitation
PHASE2Ages 18+InterventionalTreatmentDuke UniversityInvestigator-initiated
~50 participants
Updated 2026-06-10 on ClinicalTrials.gov
What's tested:Transcranial Magnetic Stimulation (TMS)Placebotrihexyphenidyl 10mg
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Neck Angles as Measured by Neck Sensor Device
Measured over Baseline, approximately 24 weeks (in person visit 8)
Conditions
Where it's being run
1 sites across 1 statesNorth Carolina1
Study leadership
- Noreen Bukhari-Parlakturk, MD PhD · PRINCIPAL_INVESTIGATOR · Duke Health
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
18yrs and older
Diagnosed with isolated cervical dystonia by Neurologist
Must be able to sign an informed consent
Must be literate
18yrs and older
diagnosed with cervical dystonia by a Neurologist
must be able to sign informed consent
must be literate
On no medications or one medication to treat symptoms of dystonia for a minimum of one month prior to study participation
Exclusion
Other neurological movement disorders diagnoses including other types of dystonia, Parkinsonism, or essential tremor
History of seizure disorder
Concomitant medications known to decrease seizure threshold
Illicit drug use
No TMS therapy for another indication within one month of this research study
Botulinum toxin injections within 3 months of the research study
Medications used for symptom treatment of dystonia including anticholinergic, benzodiazepines, and muscle relaxants among others within one month of the study
No physical or occupational therapy of the neck within one month of the study
Any contraindications to MRI or TMS
other neurological movement disorders diagnoses including Parkinsonism, or essential tremor
botulinum toxin injections within 3 months of research study
More than two medications used for symptom treatment of dystonia including anticholinergic, benzodiazepines, and muscle relaxants among others within one month of the study
contraindications to MRI or TMS
a history of seizures and anti-seizure medications by review of medical records
What this trial measures
- Change in Neck Angles as Measured by Neck Sensor DeviceBaseline, approximately 24 weeks (in person visit 8)
Mixed modeling will be used to compare the degree of neck angle movements between active TMS, sham TMS, and baseline visits.