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Cognitive Training for Mild Cognitive Impairment in African Americans

This study is testing two behavioral interventions for Mild Cognitive Impairment (MCI), a condition where people have memory or thinking problems that are more than normal aging but not as severe as dementia. One intervention is called Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (ME-CCT), which uses techniques to help with memory, attention, and planning. The other is Race Based Stress and Empowerment Focused Compensatory Cognitive Training for Mild Cognitive Impairment (RBSEF-CCT-MCI), which adds ways to cope with race-related stress to the ME-CCT program. The study aims to see if these programs improve verbal learning and memory, attention, and processing speed over eight weeks. You may be able to join if you are 65 or older, identify as Black/African American, and can travel to Rosalind Franklin University. The study plans to enroll 9 participants.

Study design
This is an interventional study, meaning participants will receive a specific treatment. It is a pilot open trial, with 8-10 participants per group.
What's involved
Participants will receive group-based intervention for 8 weeks. You will need to travel to Rosalind Franklin University.
Compensation
Not stated in the trial record.
Follow-up
The primary outcomes, such as verbal learning and memory, will be measured at up to eight weeks.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06330844

Race-Based Stress and Cognitive Training for MCI

Recruiting
NAAges 65+InterventionalTreatment
Rosalind Franklin University of Medicine and Science
~9 participants
Updated 2025-07-24 on ClinicalTrials.gov
What's tested:Race Based Stress and Empowerment Focused Compensatory Cognitive Training for Mild Cognitive Impairment (RBSEF-CCT-MCI)Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (ME-CCT)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Verbal learning and memory
Measured over up to eight weeks
+10 more outcomes measured

Conditions

Mild Cognitive Impairment

Explore related trials

Mild cognitive disorder

NCT06330844

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Rosalind Franklin University of Medicine and Science

    Chicago, Illinoisstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Rachael L Ellison, PhD · PRINCIPAL_INVESTIGATOR · Rosalind Franklin University of Medicine and Science

Who to contact

Rachael L Ellison, PhD
[email protected]
(847) 578-3000
Email the study team

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Eligibility criteria

Inclusion

The study will be conducted in-person, so they must be able to travel to Rosalind Franklin University.
The study will initially be limited to participants who self-identify as Black/African American, or who self-identify with other racial/ethnic groups in addition to self-identifying as Black/African-American; however, may be expanded to include participants that identify as Hispanic/Latine.

Exclusion

Participants are ineligible to participate in this study if they are not at least 65 years of age and are not experiencing at least mild cognitive impairment or self-reported cognitive difficulties.
Participants will also be excluded if they have a diagnosis of dementia (i.e., major neurocognitive disorder), intellectual disability, mild head injury (i.e., concussion) within the last six months, and/or a history of moderate to severe traumatic brain injury.
Diagnosis of dementia may be from self-report or other medical records, or for participants to fail screening cognitive assessments (i.e., the RBANS) that would suggest they may be at the level of dementia (i.e., major neurocognitive disorder) as ultimately determined by study PI with objective scores less then 2 standard deviations below the mean on the RBANS.

What this trial measures

  • Verbal learning and memoryup to eight weeks

    Assessed by the California Verbal Learning Test- Second Edition (CVLT-II)

  • Basic auditory attention and working memoryup to eight weeks

    Assessed by the Digit Span subtest of the Wechsler Adult Intelligence Scale (WAIS-IV)

  • Psychomotor processing speedup to eight weeks

    Assessed by the Coding and Symbol search subtests of the WAIS-IV

  • Psychomotor processing speed; executive functioningup to eight weeks

    As assessed by the Stroop Test

  • Self-report of prospective and retrospective memoryup to eight weeks

    The Prospective and Retrospective Memory Questionnaire (PRMQ). The PRMQ developed to provide a self-report measure of prospective and retrospective memory slips in everyday life. It consists of sixteen items, eight asking about prospective memory failures, and eight concerning retrospective failures.

  • Self-report of cognitive concernsup to eight weeks

    Neuro-QOL (neuro-quality of life); applied cognition: general concerns \& executive functioning (EF) subscales

  • The Patient Health Questionnaire-9up to eight weeks

    (i.e., PHQ-9; assessing self-report symptoms of depression)

  • Self-report symptoms of anxietyup to eight weeks

    As assessed by the Generalized Anxiety Disorder-7 questionnaire (i.e., GAD-7)

  • Self-reported daily functioningup to eight weeks

    As assessed by The World Health Organization Disability Assessment Schedule 2.0 (i.e., WHODAS 2.0)

  • The Racial Microaggressions Scaleup to eight weeks

    Assessing the occurrence and distress elicited by racial indignities, slights, mistreatment, or offenses that people of color may face on a recurrent or consistent basis.

  • The Trauma Symptoms of Discrimination Scaleup to eight weeks

    Self-report measure assessing the traumatizing impact of discrimination broadly by measuring anxiety-related symptoms of trauma due to discriminatory experiences