This study is testing if a brief electrical stimulation (BES) during surgery can improve nerve regrowth and smile outcomes for people with one-sided facial paralysis. You might be able to join if you are 18-80 years old and are having a specific type of surgery called a two-stage cross-face nerve graft (CFNG) for smile reanimation. The study aims to see how well nerves regenerate by looking at nerve tissue (histology) and also by evaluating smile improvements. This study is currently unclear on its recruitment status, and there are no specific biomarkers required for eligibility.

Study design

This interventional study plans to enroll 20 participants who will be randomly assigned to either receive brief electrical stimulation or standard care during surgery.

What's involved

Participants in both groups will undergo nerve biopsies during surgery. Those in the treatment group will also receive about 10 minutes of electrical stimulation during the first surgery.

Compensation

Not stated in the trial record.

Follow-up

The main goal of the study is measured at 24 months after the surgery.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.