Fiber Supplementation for Heart Failure and Type 2 Diabetes
This study is looking at how adding a fiber supplement, Bob's Red Mill Potato Starch, to your diet might affect your gut health if you have heart failure with preserved ejection fraction (HFpEF) and Type 2 diabetes. Researchers want to see if this potato starch helps the bacteria in your gut make more short chain fatty acids, which they believe could be beneficial. You may be able to join if you are an adult with stable HFpEF (meaning your heart's pumping ability is over 50%) and Type 2 diabetes with well-controlled blood sugar (glycated hemoglobin under 10%). The study aims to enroll 30 participants and will measure changes in specific short chain fatty acids in your stool and blood after about 4 weeks.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 30 participants.
- What's involved
- You will consume Bob's Red Mill Potato Starch twice a day, starting with 10 grams for 7 days, then increasing to 20 grams for approximately 3 weeks. Stool and plasma samples will be collected at the beginning and after about 4 weeks.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for approximately 4 weeks to measure changes in short chain fatty acid levels.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Scott Hummel, MD, MS · PRINCIPAL_INVESTIGATOR · University of Michigan
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Changes in Short Chain Fatty Acid (SCFA) butyrate levels - stoolBaseline, approximately 4 weeks
Stool will be analyzed.
- Changes in Short Chain Fatty Acid (SCFA) butyrate levels - plasmaBaseline, approximately 4 weeks
Plasma samples will be analyzed.
- Changes in propionate levels - stoolBaseline, approximately 4 weeks
Stool will be analyzed.
- Changes in propionate levels- plasmaBaseline, approximately 4 weeks
Plasma samples will be analyzed.
- Changes in acetate levels- stoolBaseline, approximately 4 weeks
Stool will be analyzed.
- Changes in acetate levels- plasmaBaseline, approximately 4 weeks
Plasma samples will be analyzed.