Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study)

This study is looking at ways to improve wound healing after a cesarean section (C-section). It compares two methods of cleaning the wound: using normal saline (saltwater) or using Irrisept. Irrisept is a special rinse that contains a very low concentration of chlorhexidine gluconate (CHG), an antiseptic. The study wants to see which method leads to better wound healing up to 8 weeks after surgery. You may be able to join if you are 18 or older, having a planned C-section at Loma Linda University Children's Hospital, and have certain medical conditions like obesity or diabetes. The study is currently unclear about its recruitment status.

Study design
This is an open-label, randomized study, meaning you and your doctors will know which treatment you receive. It plans to enroll 400 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your wound healing will be evaluated for up to 8 weeks after your C-section.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06339203

Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study)

Recruiting
NAAges 18+InterventionalPrevention
Loma Linda University
~400 participants
Updated 2026-06-08 on ClinicalTrials.gov
What's tested:IrriseptNormal Saline

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Composite wound evaluation scale after caesarean delivery
Measured over Up to 8 weeks postop
Cesarean Section Complications
Cesarean Section; Infection
1 sites across 1 states
California1
  • Ruofan Yao, MD, MPH · PRINCIPAL_INVESTIGATOR · Loma Linda University

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Eligibility criteria

Inclusion

Age 18 or older
Singleton pregnancy
Planned cesarean delivery at gestational age 37 weeks or later at Loma Linda University Children's Hospital
Planned post-operative follow up with Loma Linda OBGYN
Speak English or Spanish
At least one of the following medical complications: Obesity BMI\>= 30kg/m2, Diabetes, Spontaneous rupture of membranes, Intraamniotic infection

Exclusion

Emergency cesarean delivery
  • Composite wound evaluation scale after caesarean deliveryUp to 8 weeks postop

    Wound Evaluation scale will be used to evaluate appropriate healing in the following categories: redness, bruising, discharge, tissue breakdown, wound infection