Observational Study of Pacing Options for Heart Failure

This study is looking at different ways to help people with heart failure (Heart Failure With Reduced Ejection Fraction, or HFrEF) who have had issues with their heart device leads. Specifically, it compares two methods: Coronary Sinus Lead Revision and surgical Left Ventricular Epicardial Pacing. These are both ways to fix problems when the wires (leads) of a special heart device (biventricular pacing resynchronization, or BVP-CRT) stop working correctly. The study wants to see which of these two approaches is more often needed again (lead revision) right after the procedure. You might be able to join if you are over 18, have HFrEF, and have experienced a problem with your heart device lead that was then fixed using one of these two methods. The study is currently unclear on its recruitment status and plans to include 100 participants.

Study design
This is an observational study, meaning researchers will look at existing patient information rather than giving new treatments. It is a single-center, retrospective study involving 100 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, the need for lead revision, is measured at the time of the procedure.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06342492

Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead Failure

Recruiting
Not specifiedAges 18+Observational
Kansas City Heart Rhythm Research Foundation
~100 participants
Updated 2024-10-28 on ClinicalTrials.gov
What's tested:Coronary Sinus Lead Revision

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Need for lead revision
Measured over Procedure Day
Heart Failure With Reduced Ejection Fraction

NCT06342492

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Kansas City Heart Rhythm Institute

    Overland Park, Kansasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Naga Venkata K. Pothineni · PRINCIPAL_INVESTIGATOR · Kansas City Heart Rhythm Institute

Opens a ready-to-send draft in your own email app — review before sending.

Want this trial checked against your situation?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

All patients older than 18 years of age
Patients with HFrEF that underwent BVP-CRT
Experienced CS lead failure, whether initial or recurrent, subsequently replaced with transthoracic epicardial lead placement or CSP
Underwent Medtronic, Boston Scientific, or Abbott lead placement

Exclusion

Patients younger than 18 years of age
Transthoracic epicardial lead placement or CSP performed as the initial approach or for other reasons than lead replacement
Those for which CRT no longer provides symptom relief or mortality benefit.
  • Need for lead revisionProcedure Day

    Compare the need for lead revision between conduction system pacing (CSP) and transthoracic left ventricular (LV) epicardial pacing approach