Quantitative Assessment of Autologous Fat Transfer for Breast Reconstruction

This study is looking at how well different imaging methods (like photographs, ultrasound, and MRI) can track changes in the breast after autologous fat transfer (fat grafting) for reconstruction. Researchers will compare 2-D and 3-D photographs, ultrasound, and MRI scans to see how the breast changes over time. You would also complete a questionnaire (BREAST-Q™) to share your satisfaction and quality of life. The study aims to enroll 15 adults aged 18 or older who are planning to have autologous fat transfer for breast or chest wall reconstruction and can undergo an MRI. The main goal is to measure changes in breast/chest wall volume using imaging from the start of the study through about one year.

Study design: This is a single-arm pilot study, meaning all participants will receive the same intervention. It plans to enroll 15 participants.
What's involved: You would have several visits, including pre-operative appointments and follow-up visits. These visits involve 2-D and 3-D photographs, ultrasound, MRI scans, and completing a questionnaire.
Compensation: Not stated in the trial record.
Follow-up: Participants will be followed from Visit 1 through study completion, which is an average of one year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Quantitative Assessment of Autologous Fat Transfer

Recruiting

NAAges 18+Interventional

University of Chicago

~15 participants

Updated 2025-11-10 on ClinicalTrials.gov

What's tested:2-Dimensional (2-D) Photographs (Visit 1/ Follow up Visit 3-6)3-Dimensional (3-D) Photographs (Visit 1- 6)Ultrasound Soft Tissue Assessment (Visit 1/ Follow up Visit 4-6)Magnetic Resonance Imaging Volume Assessment (Visit 1/ Follow up Visit 4-6)BREAST-QTM questionnaire (Visit 1/ Follow up Visit 4-6)

At a glance

Recruiting sites

2 of 2 listed sites are recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Change from baseline in breast/chest wall following autologous fat grafting, measured by imaging.

Measured over Visit 1through study completion, an average of 1 year

Conditions

Autologous Fat Grafting

Where it's being run

2 sites across 2 states

Illinois1

Texas1

Study leadership

Summer Hanson, MD · PRINCIPAL_INVESTIGATOR · University of Chicago

Who to contact

Summer Hanson, MD

[email protected]

773-702-6302

Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime

Eligibility criteria

Inclusion

Planned autologous fat transfer or fat grafting reconstruction of the breast or chest wall.

Able to provide written or electronic informed consent.

Able to undergo MRI.

Exclusion

Vulnerable subjects (children, prisoners, pregnant women).

Patients who have active cancer, metastatic disease, solid organ transplantation / immunosuppression, or autoimmune diseases.

Unable to undergo MRI (history of metal contraindication, claustrophobia)

What this trial measures

Change from baseline in breast/chest wall following autologous fat grafting, measured by imaging.Visit 1through study completion, an average of 1 year
Images will be obtained from photographs, ultrasound, and MRI to compare and follow outcomes of autologous fat grafting to the chest for reconstruction and to visualize changes in the breast over time.

Trialytics