Evaluation of the Effects of a Nutritional Intervention of Ketogenic Medium-chain Triglycerides and B-vitamins on Cognitive Functioning in Older Adults With Mild Cognitive Impairment (COGNIKET-MCI)
At a glance
Conditions
NCT06347315
Where you'd take part
This study runs at 28 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Universitare Altersmedizin FELIX PLATTER
Basel, Basel, Switzerlandstudy coordinator listed
Recruiting
AO Card. G. Panico
Tricase, Italyno site contact published
Recruiting
AOU Policlinico Umberto I - Sapienza Università di Roma
Roma, Italyno site contact published
Recruiting
Azienda Ospedaliera SantAndrea
Roma, Italyno site contact published
Recruiting
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone"
Palermo, Italyno site contact published
Recruiting
CHU de Montpellier - Hôpital Gui de Chauliac
Montpellier, Franceno site contact published
Recruiting
CHU de Nantes - Hôpital Nord Laennec
Nantes, Franceno site contact published
Recruiting
CHU de Toulouse - Gerontopole
Toulouse, Franceno site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Preclinical Alzheimer's Cognitive Composite (PACC) score12 months
The change from baseline on the PACC composite cognitive score of episodic memory, timed executive function, and global cognition PACC has 4 components: * Free and Cued Selective Reminding Test (0 (worst)-96 (best recall); * Logical Memory Ib (Immediate Recall) from the WMS-IV (Range 0 (worst)-25 (best recall); * Wechsler Adult Intelligence scale - revised: Digit Symbol Substitution Test (DSST): (ranges 0 \[none\]-93 \[best performance\]) * Mini Mental State Examination (Range 0 \[worst\] - 30 \[best performance\]). Component scores are transformed using an established normalization method into z-scores. Each of 4 component change scores is divided by baseline sample standard deviation (SD) of that component. These z scores are summed to form the composite score. A z-score of 0 is equal to the mean and implies how many SD higher or lower score as compared with baseline score, with increase signifying improvement.