Evaluating Reduced Radiation for Coronary Angiography

This study is looking at whether a new technique can reduce the amount of radiation you receive during a coronary angiogram. A coronary angiogram is a test that uses X-rays to look at the blood vessels that supply your heart. The study will compare standard angiograms with a new method that uses very low radiation doses and special software to improve the images. Researchers want to see if these low-radiation images are just as good as those from standard angiograms. You might be able to join if you are at least 18 years old, speak English, and are scheduled for a coronary angiogram. The study is aiming to include 50 participants. The main goal is to compare the quality of the images, specifically looking at how well they show narrowing in your arteries.

Study design
This is an observational study, meaning researchers will watch and collect information without giving you a specific treatment. It plans to include 50 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary measurement of image quality will be taken during the procedure (periprocedural).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06348875

Clinical Evaluation of Radiation Reduction for Optimized Safety

Not Yet Recruiting
Not specifiedAges 18+Observational
Angiowave Imaging
~50 participants
Updated 2025-11-13 on ClinicalTrials.gov

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Segment-level percent diameter stenosis (%DS)
Measured over Periprocedural
Coronary Artery Disease
Myocardial Infarction
Coronary Disease
Coronary Stenosis
Angina Pectoris
Chest Pain
1 sites across 1 states
Michigan1
  • Aram Salzman · STUDY_CHAIR · Angiowave Imaging
  • Sean Madden, PhD · STUDY_DIRECTOR · Angiowave Imaging
  • Ryan Madder, MD · PRINCIPAL_INVESTIGATOR · Corewell Health

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Referred for clinically indicated coronary angiography
≥18 years of age
Not pregnant
English speaking
Not imprisoned
Able to provide written informed consent

Exclusion

Hemodynamically or electrically unstable.
Indication for coronary angiography is emergent, including ST-segment elevation myocardial infarction
History of coronary artery bypass grafting
An eGFR \<60
Pregnant or lactating
A BMI of 45 or greater
Any other factor that the investigator feels would put the patient at increased risk or otherwise make the patient unsuitable for participation in the protocol
  • Segment-level percent diameter stenosis (%DS)Periprocedural

    Segment-level quantitative coronary angiography (QCA) determination of percent diameter stenosis (%DS)