Understanding Chronic Pain After Surgery in Children

This study, called POPSICLE, is looking at how often children experience long-lasting pain after common surgeries, what might cause it, and how it affects their lives. There are no specific treatments being tested; instead, researchers will gather information through questionnaires from children aged 0 to 16 who are having surgeries like appendectomies, circumcisions, or orchidopexies. The goal is to understand chronic post-surgical pain (CPSP) and its risk factors, including anxiety, pre-existing pain, and how pain is managed right after surgery. This information will help doctors improve care and reduce the chance of children developing chronic pain after an operation. The study aims to enroll 5000 participants.

Study design
This is an observational study, meaning researchers will collect information without providing any specific interventions. It plans to enroll 5000 participants aged 0-16 years.
What's involved
You would complete questionnaires at six different times, starting before surgery and continuing up to 10-12 months after surgery. These questionnaires will assess pain and how you are functioning.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 10-12 months after surgery, with the primary outcome measured at 12 months.

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NCT06354699

A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children

Recruiting
Not specifiedUp to 16Observational
Telethon Kids Institute
~5,000 participants
Updated 2025-10-23 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 16 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The prevalence of chronic post-surgical pain after 10- 12 months.
Measured over 12 months
Chronic Pain
16 sites across 11 states
Australia3
Texas2
Western Australia2
Canada2
California1
Colorado1
Illinois1
Michigan1
  • Britta P von Ungern-Sternberg · PRINCIPAL_INVESTIGATOR · Telethon Kids Institute

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  • The prevalence of chronic post-surgical pain after 10- 12 months.12 months

    the prevalence of chronic post-surgical pain in paediatric patients after 10- 12 months.