Back to search results

Liver Volume Study for Upper Abdominal Cancers Undergoing SBRT

This study is looking at how changes in liver size throughout the day and after eating affect radiation treatment planning for upper abdominal cancers. When you receive Stereotactic Body Radiotherapy (SBRT), a precise type of radiation, doctors need to know the exact size and position of your liver to protect it. This study will measure your liver volume at different times after you consume a standardized high-carbohydrate meal (like an 8-ounce Ensure® nutritional protein shake). The goal is to see if these changes in liver volume could affect how accurately your radiation dose is delivered. You may be able to join if you are 18 or older and have primary upper abdominal cancer (pancreatic, bile duct, liver) or upper abdominal metastases (liver, adrenal, upper abdominal lymph nodes) that will be treated with SBRT. This study is currently unclear on its recruitment status and plans to enroll 17 participants.

Study design
This is an interventional study with a planned enrollment of 17 participants. The phase of the study is not specified.
What's involved
You will have your liver volume measured at baseline and again 4 hours after consuming a standardized high-carbohydrate meal.
Compensation
Not stated in the trial record.
Follow-up
Your liver volume will be measured at baseline and 4 hours post intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06355895

Liver Volume Variation Effect on SBRT Planning and Delivery for Upper Abdominal Malignancies

Recruiting
NAAges 18+InterventionalHealth services
University of Pittsburgh
~17 participants
Updated 2026-06-11 on ClinicalTrials.gov
What's tested:Standardized high-carbohydrate meal

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Diurnal Difference in Liver Volumes
Measured over At baseline and at 4 hours post intervention

Conditions

Upper Abdominal Malignancies

Explore related trials

Bile Duct CarcinomaLiver CarcinomaMalignant Adrenal Gland NeoplasmPancreatic CarcinomaUpper Abdominal Malignancies

Where it's being run

1 sites across 1 states
Pennsylvania1

Study leadership

  • Susannah Ellsworth, MD · PRINCIPAL_INVESTIGATOR · UPMC Hillman Cancer Center

Who to contact

Samantha Demko, BSN
[email protected]
412-623-1400
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Exclusion

Had prior Radiation Therapy to the liver
Contraindication to receipt of iodinated IV contrast for CT (such as renal insufficiency or allergy that cannot be overcome by premedication)
Pregnancy/lactation OR woman of childbearing potential who is unable or unwilling to use adequate contraception during Radiation Therapy.
Inability to fast.

What this trial measures

  • Diurnal Difference in Liver VolumesAt baseline and at 4 hours post intervention

    Percentage diurnal difference in total liver volumes (change in liver volume), as measured by Stereotactic Body Radiation Therapy (SBRT) planning software.