Computerized Decision Support to Prevent Stroke in Atrial Fibrillation
This study is looking at a new way to help prevent strokes in people with atrial fibrillation (AF), a condition where the heart beats irregularly. It's testing an "Alert-based computerized decision support" system. This system will show an on-screen alert to doctors during appointments if their patient with AF is at high risk for stroke but isn't taking blood thinners (anticoagulation) to prevent it. The goal is to see if these alerts help more high-risk AF patients get a prescription for anticoagulation within 90 days. Researchers will also track how often major bleeding occurs within 6 months. You might be able to join if you are 18 or older, have AF, and a specific risk score (CHA2DS2VASc score of 2 or more for males, 3 or more for females), and are not currently taking blood thinners. The study plans to include about 2500 people, but its current status is unclear.
- Study design
- This is an interventional study, meaning participants will receive a specific intervention. It plans to enroll 2500 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Researchers will follow up on anticoagulation prescriptions at 90 days and major bleeding at 6 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Computerized Decision Support to Prevent Stroke in Atrial Fibrillation
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Gregory Piazza, MD, MS · PRINCIPAL_INVESTIGATOR · Brigham and Women's Hospital
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Frequency of prescription of anticoagulation at 90 days in high-risk AF patients in the outpatient setting who are not being prescribed anticoagulation for stroke prevention at the time of study enrollment90 days
The primary efficacy outcome will be determined by review of the Electronic Health Record (EHR) medication documentation for prescription of anticoagulation by 90 days after enrollment. These data will be collected in the form of a BPA report and then confirmed by independent data abstractors.
- Frequency of major bleeding at 6 months from enrollment.6 months
Defined by the ISTH bleeding classification system. These data will be confirmed by independent data abstractors and then independently adjudicated by a blinded 3-physician expert Clinical Events Committee.