Back to search results

FORCES Study: Foods & Oil to Repair, Correct and Enhance Strength for Sarcopenia

This study, called FORCES, is looking at whether certain foods can help older adults with sarcopenia (muscle weakness and loss). You would eat two food products daily for 24 weeks. One group will receive foods with high linoleic acid from safflower oil, and another group will receive foods with high oleic acid from safflower oil. Researchers will measure changes in your leg muscle strength to see if these foods help. To join, you must be between 65 and 80 years old, have probable sarcopenia, and have low linoleic acid intake. People with certain stomach or gut issues cannot participate. The study aims to enroll 66 participants.

Study design
This is a randomized, placebo-controlled study with two groups. It plans to enroll 66 participants.
What's involved
You would consume two specific food products daily for 24 weeks. Muscle strength will be measured at the start and end of this period.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 24 weeks, with the primary measurement taken at Week 24.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06361511

The Foods & Oil to Repair, Correct and Enhance Strength (FORCES) Study

Recruiting
NAAges 65–80InterventionalTreatment
Ohio State University
~66 participants
Updated 2026-04-21 on ClinicalTrials.gov
What's tested:High Linoleic Acid FoodsHigh Oleic Acid Foods

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Changes is leg extensor muscle strength
Measured over Week 0 and Week 24

Conditions

Sarcopenia

Explore related trials

Sarcopenia

Where it's being run

1 sites across 1 states
Ohio1

Study leadership

  • Martha Belury, PhD RDN · PRINCIPAL_INVESTIGATOR · Ohio State University

Who to contact

Martha Belury, PhD RDN
[email protected]
614-292-1680
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

Linoleic Acid Intake \<75% of the adequate intake
Probable sarcopenia

Exclusion

Gastrointestinal diseases or disorders (including pancreatic and gastric bypass surgery) where consumption of the study foods would be contraindication or where the disease or disorder could negatively affect nutrient absorption and/or would prevent participants from tolerating the study foods
Hyperthyroidism diagnosis
Food Allergy or intolerances
Any dietary restriction where consumption of the study foods or any ingredient would be contraindicated
Unstable management of heart failure, heart disease events (including stroke or heart attack) within last 3 months prior to enrollment, a plan for heart surgeries or cardiac procedures
Current or previous diagnosis of severe kidney failure, liver cirrhosis, other liver diseases/infections that cause liver damage and some pulmonary diseases or severe/uncontrolled pulmonary diseases
Severe or uncontrolled rheumatologic or orthopedic diseases
Current diagnosis of or current treatment of cancer other than non-melanoma skin cancer
Neuromuscular or neurological conditions or diseases or use of mobility assistance (wheelchair, walker etc..) that would impact movement needed to perform the muscle function tests or prevent completion of the muscle function tests
Use of mobility assistance (wheelchair, walker etc..) that would prevent completion of the muscle function tests
Current use of supplements or medications for weight loss or following a weight loss program
Use of supplements high in linoleic acid in the past 4 weeks prior to enrolling
Pregnancy and lactation
Alcohol or drug abuse
Allergy/intolerance to lidocaine or similar medication
Use of anticoagulant, antiplatelet, or other blood thinner medications
Terminal Illness
Any condition leading to muscle loss or weakness, impaired mobility or range of motion in legs (excluding normal aging)

What this trial measures

  • Changes is leg extensor muscle strengthWeek 0 and Week 24

    To determine the impact of high linoleic safflower oil on isokinetic leg extensor muscle strength through isokinetic dynamometer