Understanding and Improving FND Treatment at UAB

This study at the University of Alabama at Birmingham (UAB) aims to create and evaluate a better way to treat Functional Neurological Disorder (FND), including conditions like non-epileptic seizures. It involves different healthcare professionals like psychiatrists, speech, physical, and occupational therapists working together. The goal is to understand how well this new treatment approach works by looking at information like your demographics, anxiety and depression levels (measured by the Hospital Anxiety and Depression Scale or HADS), and how your daily functioning changes over 4 months. You could be eligible if you are 8 to 89 years old, can read and write English, and are referred for FND treatment at UAB or Children's of Alabama.

Study design
This is an observational study planning to enroll 1100 participants, including adults and children with their parents/guardians.
What's involved
You will complete pre-treatment surveys and during outpatient visits, your clinician will record symptom frequency and a global improvement scale.
Compensation
Not stated in the trial record.
Follow-up
Your progress will be assessed at 4 months after starting the program.

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NCT06362161

Establishment of an Interdisciplinary Functional Neurological Disorder (FND) Treatment Program and Development of a Clinical Care Pathway for FND

Recruiting
Not specifiedAges 8–89Observational
University of Alabama at Birmingham
~1,100 participants
Updated 2026-06-11 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patient Demographic Information
Measured over 4 months
+18 more outcomes measured
Functional Neurological Disorder
Convulsion, Non-Epileptic
Functional Seizure
1 sites across 1 states
Alabama1
  • Aaron Fobian, PhD · PRINCIPAL_INVESTIGATOR · University of Alabama at Birmingham

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Eligibility criteria

Inclusion

Diagnosis of FND
Can read and write English fluently
Referred to UAB outpatient treatment for FND in physical, occupational, or speech therapy
Referred to UAB outpatient treatment for FND in psychiatry
Referred to inpatient consult for FND at Children's of Alabama or UAB Hospital
Parent/guardian willing to participate in the study with a pediatric patient

Exclusion

Unable to read or write English fluently
  • Patient Demographic Information4 months

    Includes questions regarding patient's demographic information, referring physician, current symptoms, medical history, and recent functioning including work and school missed, mobility aids used, or receipt of disability service. Completed by adult FND patients and parent/guardian of pediatric FND patients during the intake therapy session before beginning treatment and after completing FND treatment.

  • Hospital Anxiety and Depression Scale (HADS)4 months

    HADS is a self-assessment scale for detecting states of depression and anxiety in the setting of an outpatient hospital. Score ranges from 0-21 for depression and anxiety respectively and higher scores indicate greater anxiety and depression. Completed by adult patient before beginning treatment and after completing treatment.

  • ASM 121 functional assessment definitions4 months

    Assesses activities of daily living. Scores ranges from 12-60; higher scores indicate greater difficulty in performing daily activities. Completed by adult patient before beginning treatment and after completing treatment.

  • SF-36 (subjective health and wellbeing)4 months

    Assesses physical functioning, bodily pain, role limitations due to physical health problems, role limitations due to personal or emotional problems, emotional well-being, social functioning, energy/fatigue, and general health perceptions. Completed by adult patient before beginning treatment and after completing treatment.

  • Work and Social Adjustment Scale (WSAS)4 months

    Assesses impairment in functioning. Score ranges from 0-40; higher scores indicate severe functional impairment. Completed by adult patient before beginning treatment and after completing treatment.

  • Patient Health Questionnaire 154 months

    Assesses patient's physical symptom severity. Scores ranges from 0-30; higher scores indicate severe somatoform disorder. Completed by adult patient before beginning treatment and after completing treatment.

  • Dizziness Handicap Inventory4 months

    Assesses functional, physical and emotional problems related to dizziness, specifically considering their condition in the last month. Scores range from 0-100; higher scores indicate severe handicap. Completed by adult FND patient and pediatric patients and their parent/guardian before beginning treatment and after completing treatment.

  • Dizziness Symptom Profile4 months

    Assesses severity of dizziness. Score ranges from 0-124; higher scores indicate severe impairment due to dizziness. Completed by adult patient, and pediatric patient and their parent/guardian before beginning treatment and after completing treatment.

  • Adult Tic Questionnaire (ATQ)4 months

    The ATQ is a brief self-report questionnaire that provides information regarding frequency, intensity, and severity of vocal and motor tics. Completed by adult patient before beginning treatment and after completing treatment.

  • Child Self-Report Tic Questionnaire4 months

    The child self-report tic questionnaire is a brief self-report questionnaire that provides information regarding frequency, intensity, and severity of vocal and motor tics.Completed by pediatric patient before beginning treatment and after completing treatment.

  • Parent Tic Questionnaire (PTQ)4 months

    The PTQ assesses tic severity, frequency and intensity in the past week, allowing for individual parent ratings of tic presence or absence for 14 vocal tics and 14 motor tics.Completed by parent/guardian of pediatric patients before beginning treatment and after completing treatment.

  • Seizure Questionnaire4 months

    Assesses any functional seizure the patient is experiencing. Completed by adult FND patients, pediatric patients and their parent/guardian before beginning treatment and after completing FND treatment.

  • Level 2-Somatic Symptom report4 months

    Measures symptom severity in children; scores ranges from 0-26, higher scores indicate greater symptom severity. Completed by pediatric patient and parent/guardian before beginning treatment and after completing treatment.

  • Revised Children's Anxiety and Depression Scale (RCADS)4 months

    Measures anxiety and depression symptoms in children; total score ranges from 0-141, higher scores indicate increased symptom severity. Completed by pediatric patient and parent/guardian before beginning treatment and after completing treatment.

  • Functional Disability Inventory (FDI)4 months

    Measures physical functioning and disability in children with chronic pain; score ranges from 0-60, higher scores indicate greater perceived functional disability. Completed by pediatric patient and parent/guardian before beginning treatment and after completing treatment.

  • Impact on the Family Scale4 months

    Assesses parental perceptions of the impact of a child's medical condition on the family (assesses impact on financial burden, familial/social impact, personal strain and mastery); higher scores indicate greater financial burden on the family. Completed by pediatric patient and parent/guardian before beginning treatment and after completing treatment.

  • Pediatric Quality of Life (Peds-QL)4 months

    Assesses quality of life, greater scores indicate greater quality of life. Scores range from 0-100. Completed by pediatric patient and parent/guardian before beginning treatment and after completing treatment.

  • Healthcare Utility Questionnaire4 months

    Assesses patients visits to a physician's office or emergency room related to their FND symptoms. Completed by adult patient, and pediatric patient and their parent/guardian throughout the study.

  • Assessment of control over symptoms4 months

    Single question that assesses the control patients have over their symptoms. Completed by adult patient, and pediatric patient and their parent/guardian before beginning treatment and after completing treatment.