Intravenous Iron Versus Oral Iron for Iron Deficiency Anemia in Pregnancy
This study is looking at whether giving iron through a vein (intravenous Venofer 200 MG Per 10 ML Injection) early in pregnancy works better than taking iron by mouth (oral Ferrous sulfate) for pregnant women with iron deficiency anemia. Iron deficiency anemia means you don't have enough healthy red blood cells because of low iron. The study wants to see if intravenous iron can raise your hemoglobin levels (a protein in red blood cells that carries oxygen) before delivery and reduce the need for blood transfusions. You could join if you are a woman over 18, have low ferritin levels (a protein that stores iron), are pregnant with one baby up to 36 weeks, and plan to deliver at Arrowhead Regional Medical Center (ARMC). The study will measure your hemoglobin and ferritin levels before treatment and again four weeks later, and your hemoglobin level at delivery.
- Study design
- This is an interventional study, meaning participants will receive a specific treatment. About 900 pregnant women will be randomly assigned to receive either intravenous or oral iron.
- What's involved
- You would complete a symptom questionnaire, have blood tests for hemoglobin and ferritin before treatment, and then have follow-up visits with symptom checks and lab tests four weeks later and again between 24 and 28 weeks of pregnancy. Your final hemoglobin level will be checked before delivery.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your hemoglobin and ferritin levels will be measured four weeks after starting treatment, and your hemoglobin level will be measured at the time of delivery.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia
At a glance
Conditions
NCT06366698
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Arrowhead Regional Medical Center
Colton, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
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Inclusion
Exclusion
What this trial measures
- Hemoglobin differenceHemoglobin level obtained prior to treatment and then 4 weeks later
Change in hemoglobin level after intervention, larger difference mean more improvement in Hgb
- Ferritin differenceFerritin level obtained prior to treatment and then 4 weeks later
Change in ferritin level after intervention, larger difference mean more improvement in ferritin level
- Delivery HemoglobinObtained at time of delivery
Comparing pre-delivery hemoglobin levels
- Rates of blood transfusionAt time of delivery until 6 weeks postpartum
Comparing rates of blood transfusion at time of delivery between the 2 groups. The number of units transfused will be collected and compared among the groups
- Symptoms4 weeks
Comparing number of anemia symptoms before and after treatment. There are 11 anemia symptoms on the questionnaire. Using a Likert scale from 0 (no symptoms) to 5 (severe symptoms) patient mark each one. The score is totaled up and can range from 0-55.