Hepatitis C Treatment in Pregnancy

This study is looking at how well a hepatitis C (HCV) treatment called glecaprevir-pibrentasvir works for pregnant women who have a history of drug use. Researchers want to see if women take all their medication as prescribed and complete the full 56-day treatment. The study also aims to understand women's experiences with HCV treatment during pregnancy. You may be able to join if you are a pregnant woman, 18 or older, with hepatitis C and a history of past or current drug use. The study is currently unclear on its recruitment status.

Study design
This is an observational study, meaning researchers will watch and collect information without assigning treatments. It plans to enroll 50 participants.
What's involved
You would have four in-person visits over approximately one year. These visits include getting information about HCV treatment, blood tests, and completing questionnaires about your medication.
Compensation
Not stated in the trial record.
Follow-up
You will have a final study visit 4 weeks after completing HCV treatment to check for the virus, and medication adherence and treatment completion rates will be measured at 2 years.

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NCT06367465

Feasibility and Acceptability of HCV Treatment in Pregnancy

Recruiting
Not specifiedAges 18+Observational
Washington University School of Medicine
~50 participants
Updated 2026-06-09 on ClinicalTrials.gov
What's tested:Glecaprevir-pibrentasvir

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Medication adherence and treatment completion rates.
Measured over 2 years
Hepatitis C
Pregnancy Complications
2 sites across 1 states
Missouri2

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Eligibility criteria

Inclusion

Female patients ≥ 18 years old, pregnant at the time of study intake, diagnosed with hepatitis c virus infection and a history of past or current drug use.
  • Medication adherence and treatment completion rates.2 years

    The primary objective of this study is to assess patient adherence and treatment completion rates of women with a history of past or current drug use who receive initiation of Hepatitis C Virus treatment with glecaprevir-pibrentasvir during pregnancy. The primary objective of this study is to assess patient adherence and treatment completion rates of women with a history of past or current drug use who receive initiation of Hepatitis C Virus treatment with glecaprevir-pibrentasvir during pregnancy.