This study is looking into how a single dose of psilocybin (1-30 mg) might affect the brains of healthy older adults, aged 60 to 85. Researchers want to see if psilocybin can change brain structure and activity, and how this might relate to thinking, emotions, and how you predict things. You would be randomly assigned to receive a dose of psilocybin. The main way success is measured is by looking at changes in your brain structure using MRI scans at the start, one week, and four weeks after treatment. The study is currently recruiting 40 participants.

Study design

This interventional study plans to enroll 40 participants. You would be randomly assigned to receive a dose of psilocybin.

What's involved

You would need to attend all study visits, preparatory and follow-up sessions, and complete all study evaluations. This includes cognitive exams, perceptual tasks, brain imaging (MRI, DWI, fMRI), and surveys.

Compensation

Not stated in the trial record.

Follow-up

Your brain structure will be measured at baseline, one week, and four weeks after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.