PTSD Treatments for Sexual and Gender Minority Populations

This study is comparing two established therapies, Cognitive Processing Therapy and STAIR Narrative Therapy, to see how well they treat post-traumatic stress disorder (PTSD) in adults who identify as sexual and/or gender minorities (LGBTQIA+). The goal is to understand if these treatments reduce PTSD symptoms, improve quality of life, and lessen depression in this community. Researchers also want to see if factors like stress from discrimination or drug/alcohol use affect treatment outcomes, and if different groups within the LGBTQIA+ community respond differently. The study plans to enroll 400 participants and is currently unclear on its recruitment status.

Study design
This interventional study will compare two behavioral therapies in 400 participants. It aims to find out which treatment works best for LGBTQIA+ individuals.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 12 months, with assessments at months 0 (baseline), 3, 6, and 12.

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NCT06367764

A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations

Recruiting
NAAges 18+InterventionalTreatment
Stanford University
~400 participants
Updated 2025-04-24 on ClinicalTrials.gov
What's tested:Cognitive Processing TherapySTAIR Narrative Therapy

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Posttraumatic Stress Disorder (PTSD) Symptoms Measured by PTSD Checklist for DSM-5 (PCL-5)
Measured over Months 0 (baseline), 3, 6, and 12
PTSD
2 sites across 1 states
California2
  • Annesa P Flentje, PhD · PRINCIPAL_INVESTIGATOR · Stanford University

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  • Change in Posttraumatic Stress Disorder (PTSD) Symptoms Measured by PTSD Checklist for DSM-5 (PCL-5)Months 0 (baseline), 3, 6, and 12

    The PCL-5 is a validated measure of self-report DSM-5 symptoms of PTSD. The self-report rating scale is 0-4 for each symptom, with higher scores indicating greater symptom severity.