NCT06369571
Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet
Enrolling by Invitation
PHASE1Ages 18+InterventionalTreatmentJohns Hopkins UniversityInvestigator-initiated
~22 participants
Updated 2025-10-09 on ClinicalTrials.gov
What's tested:Atorvastatin 10mgModification of dietary fat composition
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Diet adherence as assessed by 3 day food records
Measured over 12 weeks
+4 more outcomes measured
Conditions
Where it's being run
1 sites across 1 statesMaryland1
Study leadership
- Tanya J McDonald, MD, PhD · PRINCIPAL_INVESTIGATOR · Johns Hopkins University
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
What this trial measures
- Diet adherence as assessed by 3 day food records12 weeks
Diet adherence will be based on the ability to achieve 10% reduction in dietary energy from saturated fat assessed from 3-day food records, the gold standard for diet intake assessments.
- Statin Adherence12 weeks
Statin adherence will be determined based on pills returned at study completion, with participants labeled adherent if 80% or more of pills were consumed.
- LDL Change12 weeks
12-week % LDL change from baseline within arms and between arms
- Change in weekly seizure frequency12 weeks
12-week difference in weekly seizure frequency from baseline
- Seizure severity questionnaire score12 weeks
12-week difference in seizure severity questionnaire (SSQ) score (score 1-7, with higher score indicating more severe seizures)