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Monetary Incentive Delay Task for Adolescent Development

This study is looking at how the brain responds to rewards in adolescents aged 14 to 17. Researchers will use a special brain scan called functional Magnetic Resonance Imaging (fMRI) while participants complete a "Monetary Incentive Delay Task." This task helps measure brain activity when you anticipate and receive rewards or losses. The main goal is to see how much brain activation (BOLD signal) occurs during this task. This study hopes to understand how brain mechanisms, like dopamine function, might be linked to substance use in young people. You can join if you are 14-17 years old, speak English, and can give your permission. The study is currently unclear on its recruitment status.

Study design
This is an observational, longitudinal study planning to enroll 300 participants (150 males and 150 females).
What's involved
You would have three in-person visits over 36 months, including brain scans and assessments. You would also complete remote substance use assessments every 90 days for 36 months.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for 36 months after the baseline assessment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06369623

Monetary Incentive Delay Task for Probing Reward-related Neural Processes

Recruiting
NAAges 14–17Interventional
Stony Brook University
~300 participants
Updated 2025-05-15 on ClinicalTrials.gov
What's tested:Monetary Incentive Delay Task

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Amount of Brain Activation (BOLD Signal) during Monetary Incentive Delay Task by Condition
Measured over Baseline, 18-month, 36-month.

Conditions

Adolescent Development

Explore related trials

Healthy Volunteers

NCT06369623

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Stony Brook Medicine

    Stony Brook, New Yorkstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Greg Perlman, PhD
[email protected]
1-631-638-1922
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

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Eligibility criteria

Inclusion

Males and females ages 14-17 years-old;
English-speaking for assent and interview completion;
Capacity to provide assent.

Exclusion

current (within 6 months) use of medication that may affect cerebral function
history of severe medical or neurological illness, including stroke or seizure;
history of head trauma with loss of consciousness;
presence of metal in the body;
pregnancy or breastfeeding;
recent drug or alcohol use determined by positive urine toxicology or breathalyzer (to validate self-report assessment of substance use history);
lifetime use of psychotropic or other medication that could likely influence dopamine function, namely stimulant medication or antipsychotic medication, except a subgroup of 25 youth with history of prescribed stimulant medication and a subgroup of 15 youth with history antipsychotic medication will be enrolled for comparison purposes.

What this trial measures

  • Amount of Brain Activation (BOLD Signal) during Monetary Incentive Delay Task by ConditionBaseline, 18-month, 36-month.

    fMRI activation during task during win, loss, and no change conditions, as well as anticipation and consummation phases.