Soluble Fiber for Asthma in Children
This study is looking at how a soluble fiber called inulin (Fruitafit Inulin) might affect asthma in children aged 6 to 17. You might be able to join if you have an asthma diagnosis from the last two years and either a high FeNO (fractional exhaled nitric oxide, a measure of airway inflammation) or a history of environmental allergies. The study wants to see if increasing fiber intake can change the types of microbes in your gut and potentially improve asthma. Success in this study will be measured by changes in "alpha diversity," which refers to the variety of bacteria in your gut, after 6 weeks. The current recruitment status is unclear.
- Study design
- This is a randomized controlled trial, meaning participants will be randomly assigned to receive either inulin or a placebo. The study plans to enroll 105 children.
- What's involved
- You would complete a diet questionnaire, have a nasal wash, and have your blood drawn. You'll also provide three stool samples over approximately 30 days and have a second study visit.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary endpoint is measured at 6 weeks, and the total study time is approximately 30 days.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
A Clinical Trial of Soluble Fiber for Asthma
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Matthew Rank · PRINCIPAL_INVESTIGATOR · Phoenix Children's
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Alpha diversity.6 weeks
A total of 84 participants is required to find significant difference of 54 units of Richness at 90% power with a small effect size. Alpha diversity is used to measure the abundance that individual microbes can be observed. Statistical analysis is used to generate the significance of stool sample diversity as well as how many participants are needed to see the marker.