E-cigarettes and Nicotine Pouches for Smokers
This study is for people who smoke cigarettes regularly and have tried to quit many times without success. It aims to see if switching to e-cigarettes (ECIGS) or oral nicotine pouches (ONPS) can help reduce cigarette smoking. You would be given either e-cigarettes or nicotine pouches and asked to use them instead of regular cigarettes for six weeks. Researchers will measure how many cigarettes you smoke during this time and at a follow-up later. To join, you need to be at least 21 years old, smoke at least 5 cigarettes a day, and have tried to quit smoking at least 5 times before. The study is currently unclear on its recruitment status.
- Study design
- This study is interventional and plans to enroll 200 participants. You would be randomly assigned to either the e-cigarette group or the oral nicotine pouch group.
- What's involved
- You would switch from smoking cigarettes to using either e-cigarettes or oral nicotine pouches for six weeks. There will be laboratory visits on days 6 and 7, and a 6-month follow-up.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your cigarette smoking will be measured at 19 weeks (Day 50-6-Month Follow-Up) after the initial 6-week switch period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Cigarette Consumption42 days (days 8 - 49)
The primary outcome is the longitudinal daily count of cigarettes from baseline to the end of the switch phase. Daily cigarette consumption will be determined by counting the daily spent cigarette filters returned for each of the 42 days (days 8 - 49).
- Cigarette Smoking Across Follow-Up19 Weeks (Day 50-6-Month Follow-Up)
Average cigarettes per day at the 6-month follow-up is a secondary endpoint, measured by the valid and reliable timeline follow-back (TLFB) interview.