Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography
{ "ATHERO-RT: Real-Time Atherosclerosis Activity After Thoracic Radiotherapy", "This study is looking at how radiation therapy to the chest might affect your heart's arteries. Researchers will use a special scan called 18-F-NaF Cardiac PET/MRI (Positron Emission Tomography/Magnetic Resonance Imaging) to see changes in your arteries before and after radiation. They are also using a CT Angiogram (a special X-ray to look at blood vessels) at the start. This study is for people aged 18 or older who have cancer that has spread a little (oligometastatic disease) and are having radiation therapy to their chest, where the heart will be in the treatment area. The main goal is to see if these imaging methods can successfully detect changes in atherosclerosis (hardening of the arteries) after radiation. This is a small pilot study with 10 participants, and its current status is unclear.", "design": "This is a small, single-arm study, meaning all participants receive the same interventions. It plans to enroll 10 participants.", "commitments": "You would receive an 18-F-NaF Cardiac PET/MRI and a CT Angiogram at the beginning of the study. You would have another 18-F-NaF Cardiac PET/MRI 6 months after your radiation therapy is finished.", "compensation": "Not stated in the trial record.", "follow_up": "You will be followed for 6 months after completing your radiation therapy to assess the feasibility of the imaging.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography
At a glance
Conditions
NCT06373497
Where you'd take part
This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Cedars Sinai Medical Center
Los Angeles, Californiastudy coordinator listed
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Katelyn Atkins, MD, PhD · PRINCIPAL_INVESTIGATOR · Cedars-Sinai Medical Center
Who to contact
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Inclusion
Exclusion
What this trial measures
- Feasibility of using F-NaF PET/MRI imaging6 Months
To determine the feasibility of using 18F-NaF PET/MRI imaging for detection of real-time atherosclerosis activity in patients at high risk of RT-associated cardiac dysfunction.