Observational Study for Retinal Degeneration Vision Assessments

This study is looking at how well different vision tests work for people with certain eye conditions like Retinitis Pigmentosa, Choroideremia, Stargardt Macular Dystrophy, Stargardt Disease, and Geographic Atrophy from Age-related Macular Degeneration. Researchers want to see how these tests relate to daily activities and how accurately they measure changes in vision over time. You could be eligible if you have one of these conditions and your best-corrected vision is between 20/70 and Hand Motion (HM) in at least one eye. This study does not involve any new treatments or medications; it focuses on improving how we measure vision in people with low vision. The goal is to make sure vision tests are as helpful and accurate as possible.

Study design
This is an observational study involving up to 120 participants. It is designed to evaluate vision assessments in people with various retinal conditions.
What's involved
You would attend an initial visit for a series of vision tests, followed by another visit up to two weeks later, and then periodically for up to one year.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed periodically for up to one year after their initial visit.

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NCT06375239

Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal Degeneration

Recruiting
Not specifiedAges 18+Observational
Ray Therapeutics, Inc.
~120 participants
Updated 2025-01-08 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Operational feasibility of testing moderate to profound vision impaired patients with various retinal dystrophies on a battery of visual assessments
Measured over 3 months
Retinitis Pigmentosa
Choroideremia
Stargardt Macular Dystrophy
Stargardt Disease
Geographic Atrophy from Age-related Macular Degeneration
X-lined Retinoschisis
Retinal Dystrophies
1 sites across 1 states
California1

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Eligibility criteria

Inclusion

Diagnosis of bilateral retinitis pigmentosa, choroideremia, Stargardt macular dystrophy, geographic atrophy from age-related macular degeneration, X-linked retinoschisis or other retinal dystrophies confirmed from previous eye examination records
Best-corrected visual acuity between 20/70 and HM in at least one eye as tested with clinic-based visual acuity method
Reasonably fluent in English

Exclusion

Cognitive impairment, memory loss or dementia sufficient in severity to preclude informed consent or in the opinion of the investigator would prevent satisfactory completion of some or all of the testing.
Any circumstance that in the opinion of the investigator, would interfere with participation in, or compliance with the study protocol
Current pregnancy as reported by patient
  • Operational feasibility of testing moderate to profound vision impaired patients with various retinal dystrophies on a battery of visual assessments3 months

    Determining how many patients in the visual range 20/70 - HM (depending upon indication) can perform specific tests of visual function with a measurable score.