Investigating Assisted Hatching Timing for Infertility Treatment

This study is looking at the best time to perform Laser Assisted Hatching, a procedure used in in vitro fertilization (IVF) to help an embryo implant. Researchers are comparing performing this procedure on Day 3 (cleavage stage) versus Day 5, 6, or 7 (blastocyst stage) of embryo development. The goal is to see if timing affects the "blastulation rate" (how often embryos develop into blastocysts), measured one week after egg retrieval. You may be able to join if you are a woman between 18 and 42 years old, undergoing IVF with a plan for a frozen embryo transfer, and meet specific criteria for ovarian health and BMI. The study's current status is unclear.

Study design
This is an interventional study planning to enroll 75 participants. Each participant's fertilized eggs will be split into two groups, with one group receiving Day 3 assisted hatching and the other receiving Day 5, 6, or 7 assisted hatching.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, blastulation rate, is measured one week after vaginal oocyte retrieval (VOR).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06377917

Investigating Micro-Manipulation Procedures for Assisted Hatching Timing

Recruiting
NAAges 18–42Interventional
Reproductive Medicine Associates of New Jersey
~75 participants
Updated 2026-06-03 on ClinicalTrials.gov
What's tested:Laser Assisted Hatching

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Blastulation Rate
Measured over 1 week after vaginal oocyte retrieval (VOR)
Infertility
1 sites across 1 states
New Jersey1
  • Jason Fransiak, MD · PRINCIPAL_INVESTIGATOR · Reproductive Medicine Associates of New Jersey
Christine V Whitehead, MS, BSN, RN
Email the study team

Opens a ready-to-send draft in your own email app — review before sending.

  • Blastulation Rate1 week after vaginal oocyte retrieval (VOR)

    Blastulation rate per 2 pronuclei (PN) in each group