Glycyrrhizin for Prostate Cancer
This study is testing Glycyrrhizin (GLY) in men with prostate cancer who are planning to have surgery. You would either receive 75 mg of Glycyrrhizin daily, 150 mg of Glycyrrhizin daily, or no Glycyrrhizin, for about 5 weeks before your surgery. Researchers want to see if Glycyrrhizin can reduce prostate-specific antigen (PSA) levels, which is a marker for prostate cancer, before surgery. To join, you must be at least 18 years old, have prostate cancer that hasn't been treated yet, and be scheduled for a radical prostatectomy (surgery to remove the prostate). This study is looking for 60 participants, but its current recruitment status is unclear.
- Study design
- This is a pilot, randomized study where participants are assigned by chance to one of three groups. It is an interventional study, meaning participants will receive a specific treatment or observation.
- What's involved
- You would take Glycyrrhizin daily for about 5 weeks before your prostatectomy surgery. Your PSA levels will be checked after this treatment period.
- Compensation
- Not stated in the trial record.
- Follow-up
- The main goal is to check changes in PSA levels after treatment and before surgery, which is measured at 2 months.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
GU-01: Glycyrrhizin in Prostate Cancer
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Natalie Reizine · PRINCIPAL_INVESTIGATOR · University of Illinois at Chicago
Who to contact
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What this trial measures
- To evaluate anti-tumor activity of GLY by assessing changes in prostate-specific antigen (PSA) after GLY treatment administration and prior to radical prostatectomy2 months
Changes in prostate specific antigen (PSA) in patients with prostate cancer will be assessed before and after administration of GLY