Breast Cancer Screening for Individuals on Hormone Therapy

This study is looking at breast cancer screening for people who are taking hormone therapy. It aims to understand how well screening methods like mammograms and ultrasounds work for you, and to learn about your experiences and any challenges you face during screening. The study will also gather information about your hormone therapy and family cancer history. We are looking for individuals aged 30 to 75, of all genders. This includes males aged 40-75 who have been on estrogen or progesterone hormone therapy for at least 9 months, and females aged 40-75 who have used testosterone hormone therapy (even if they've had a cosmetic mastectomy, but not a full mastectomy). The study will measure callback and biopsy rates after screening, and explore your physical, cognitive, and emotional experiences, as well as any barriers to screening, over 3.5 years.

Study design
This is an observational study, meaning researchers will gather information without giving you a specific treatment. It plans to enroll 130 participants.
What's involved
You would undergo screening mammography and whole breast ultrasound. You would also complete electronic surveys and potentially participate in one-on-one interviews or a focus group.
Compensation
Not stated in the trial record.
Follow-up
The study will follow participants for 3.5 years to measure various outcomes.

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NCT06383026

Individuals on Hormone Therapy Breast Cancer Screening Pilot

Recruiting
Not specifiedAges 30–75Observational
Medical College of Wisconsin
~130 participants
Updated 2025-09-23 on ClinicalTrials.gov
What's tested:Breast Cancer ScreeningSurvey/InterviewFocus Group

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Callback and Biopsy Rates after Breast Cancer Screening
Measured over 3.5 years
+2 more outcomes measured
Breast Cancer
1 sites across 1 states
Wisconsin1
  • Chandler S Cortina, MD, MS · PRINCIPAL_INVESTIGATOR · The Medical College of Wisconsin

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  • Callback and Biopsy Rates after Breast Cancer Screening3.5 years

    Determine the callback and biopsy rates after screening imaging of the entire individuals on hormone therapy patient cohort who complete breast imaging exams.

  • Reflexive Thematic Analysis of the Physical, Cognitive, and Emotional Experience of Breast Cancer Screening in Individuals on Hormone Therapy3.5 years

    Qualitative data utilized to identify themes around health beliefs, anxiety, and the breast cancer screening experience by describing the physical, cognitive, and emotional experience (perceived seriousness, perceived susceptibility, and anxiety) of individuals on hormone therapy cohort participants who complete surveys or participate in one-on-one interviews.

  • Reflexive Thematic Analysis on the Individual & System-Level Barriers to Breast Cancer Screening3.5 years

    Qualitative date utilized to identify individual and healthcare systems-level barriers to breast cancer screening for individuals on hormone therapy who complete surveys and/or participate in one-on-one interviews and breast imaging faculty and staff who participate in focus groups.