3D DL oZTEo for Detecting Bone Changes in Inflammatory Arthritis

This study is looking at a new way to detect bone changes, called osseous erosions, in people with inflammatory arthritis. It uses a special MRI technique called oZTEo, combined with a deep learning algorithm (a type of artificial intelligence) called 3D DL. You might be able to join if you are an adult (18 or older) with inflammatory arthritis, have had hand X-rays in the last 3-6 months showing bone erosions, and are already scheduled for a hand MRI at Mayo Clinic Rochester. The study aims to see if adding 3D DL oZTEo to a standard MRI can better identify these bone erosions.

Study design
This is an interventional study planning to enroll 25 participants. It will compare standard MRI results with those from MRI using the oZTEo sequence and 3D DL algorithm.
What's involved
You would have the oZTEo pulse sequence added to your standard hand MRI examination. This additional sequence will then be analyzed using a deep learning algorithm.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint, detecting bone erosions, is measured at 1 day after the MRI.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06383585

3D DL Ozteo in the Detection of Osseous Changes in Patients With Inflammatory Arthritis

Active, Not Recruiting
NAAges 18+InterventionalDiagnostic
Mayo Clinic
~25 participants
Updated 2026-08-14 on ClinicalTrials.gov
What's tested:oZTEo

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
The binary (yes/no) presence of bony erosions as detected by hand MRI with and without the addition of the 3D DL oZTEo sequence.
Measured over 1 day
Inflammatory Arthritis
1 sites across 1 states
Minnesota1
  • Naveen Murthy, MD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

This trial hasn't published a contact. View it on ClinicalTrials.gov

Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Adult patients ≥18 years of age
Hand radiographs performed within the past 3-6 months with imaging results available for analysis
Hand radiographs confirm the presence of bony erosions
Scheduled for a hand MRI as part of their routine clinical care at Mayo Clinic Rochester
  • The binary (yes/no) presence of bony erosions as detected by hand MRI with and without the addition of the 3D DL oZTEo sequence.1 day

    The primary outcome