Personalized GI Motility Responses to Diet
This study is looking at how your body responds to different types of rye bread. Researchers want to understand how eating whole grain rye bread versus refined grain rye bread affects your digestion (gastrointestinal motility), the helpful bacteria in your gut, and important measures for heart health like blood sugar and cholesterol. You might be able to join if you are a healthy adult between 21 and 63 years old. The study aims to enroll 50 participants. Success will be measured by changes in your gastrointestinal pressure, pH levels, and temperature after eating the bread. The study status is currently unclear.
- Study design
- This is a randomized, crossover clinical trial, meaning participants will try both types of bread at different times. The study plans to enroll 50 healthy men and women.
- What's involved
- You will consume a Smartpill monitoring device, eat either whole grain or refined grain rye bread, and provide a stool sample. Your cardiometabolic health will be monitored for 8 hours after eating.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your gastrointestinal pressure, pH, and temperature will be measured from the time you consume the bread and Smartpill until you have a bowel movement, which could be 16 hours to 5 days later.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Personalized GI Motility Responses to Diet
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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Inclusion
Exclusion
What this trial measures
- Gastrointestinal Pressure (mmHg)From consumption of bread and Smartpill to deification (single meal consumption, GI motility times vary based on participant, but could be estimated from around 16 hours to 5 days)
Pressure of gastrointestinal contractions as captured by the Medtronic Smartpill capsule temperature, transit time)
- Luminal pH (pH units)From consumption of bread and Smartpill to deification (single meal consumption, GI motility times vary based on participant, but could be estimated from around 16 hours to 5 days)
pH of gastrointestinal contents as captured by the Medtronic Smartpill capsule
- Temperature (degrees celcius)From consumption of bread and Smartpill to deification (single meal consumption, GI motility times vary based on participant, but could be estimated from around 16 hours to 5 days)
Temperature in the intestinal lumen as captured by the Medtronic Smartpill capsule
- Gastrointestinal Transit Time (hours:minutes)From consumption of bread and Smartpill to deification (single meal consumption, GI motility times vary based on participant, but could be estimated from around 16 hours to 5 days)
Duration of gastrointestinal transit as captured by the Medtronic Smartpill capsule
- Blood GlucoseBaseline to 8 hours post bread and Smartpill consumption (baseline, 0.5 hours, 1 hour, 1.5 hour, 1.5 hours, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, and 8 hours)
Concentration of glucose in whole blood from finger prick as measured by the Konsung Portable Dry Biochemical Analyzer
- TriglyceridesBaseline to 8 hours post bread and Smartpill consumption (baseline, 0.5 hours, 1 hour, 1.5 hour, 1.5 hours, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, and 8 hours)
Concentration of triglycerides in whole blood from finger prick as measured by the Konsung Portable Dry Biochemical Analyzer
- Total CholesterolBaseline to 8 hours post bread and Smartpill consumption (baseline, 0.5 hours, 1 hour, 1.5 hour, 1.5 hours, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, and 8 hours)
Concentration of total cholesterol in whole blood from finger prick as measured by the Konsung Portable Dry Biochemical Analyzer
- HDL cholesterolBaseline to 8 hours post bread and Smartpill consumption (baseline, 0.5 hours, 1 hour, 1.5 hour, 1.5 hours, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, and 8 hours)
Concentration of HDL cholesterol in whole blood from finger prick as measured by the Konsung Portable Dry Biochemical Analyzer
- LDL cholesterolBaseline to 8 hours post bread and Smartpill consumption (baseline, 0.5 hours, 1 hour, 1.5 hour, 1.5 hours, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, and 8 hours)
Concentration of LDL choelsterol in whole blood from finger prick as measured by the Konsung Portable Dry Biochemical Analyzer
- Lipopolysaccharide Binding ProteinBaseline to 8 hours post bread and Smartpill consumption (baseline, 0.5 hours, 1 hour, 1.5 hour, 1.5 hours, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, and 8 hours)
Concentration of LBP in whole blood from finger prick as measured by ELISA