VNX001 for Interstitial Cystitis / Bladder Pain Syndrome

This study is testing VNX001, given directly into the bladder (intravesical administration), for people with Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS). The goal is to see how often VNX001 is used "as needed" (PRN) to treat moderate to severe bladder pain over 14 days. Researchers will also look at how safe VNX001 is and how well people tolerate it. To join, you must have already completed Study VNX001-111 and meet other requirements. The study plans to enroll about 50 participants and is currently open.

Study design
This is an open-label study, meaning both you and the study team will know you are receiving VNX001. It aims to enroll about 50 participants.
What's involved
You will have up to seven clinic visits or one clinic visit and five phone visits over 14 days. During clinic visits, you may receive VNX001 through a catheter into your bladder.
Compensation
Not stated in the trial record.
Follow-up
The primary measurement for this study is taken at 14 days.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06394830

Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS)

Recruiting
PHASE2Ages 18+InterventionalTreatment
Vaneltix Pharma, Inc.
~50 participants
Updated 2026-01-22 on ClinicalTrials.gov
What's tested:VNX001

At a glance

Recruiting sites
2 of 5 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Frequency of PRN intravesical administrations of VNX001
Measured over 14 Days
Interstitial Cystitis
Bladder Pain Syndrome
5 sites across 4 states
California2
Arizona1
Georgia1
Oregon1

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Exclusion

Phenytoin
Carbamazepine
St. John's Wort
Phenobarbital
Rifampin 23. Have had any of the following:
Bacterial cystitis within 30 days as demonstrated by a positive urine culture (≥ 105 bacteria per mL)
History of pelvic irradiation or radiation cystitis
History or presence of uterine, cervical, pelvic, rectal, ovarian, or vaginal cancer
History of benign or malignant bladder tumors
Current chemotherapy
History or presence of tuberculous cystitis
History or presence of chemical cystitis, including that due to cyclophosphamide
History or presence of urinary schistosomiasis
Bladder or ureteral calculi
Clinically significant infectious vaginitis
Currently uncontrolled genital herpes
History or presence of urethral diverticulum
Presence of bladder fistulae
History of ketamine use
  • Frequency of PRN intravesical administrations of VNX00114 Days