Intensive Patient Referral and Education Program for Advanced Chronic Kidney Disease

This study, called iPREP-RRT, is testing an intensive education program for African American patients with advanced chronic kidney disease (CKD) and high blood pressure (Hypertension). The program includes in-person and written education about CKD and treatment options like renal replacement therapy (RRT), motivational interviewing, and home blood pressure monitoring. You'll also receive text messages to help you manage your CKD. Researchers want to see if this program improves your knowledge about CKD, your ability to manage your health, and your planning for RRT. This study is for African American adults between 18 and 70 years old who are hospitalized with advanced CKD (Stage 3B or above, or eGFR less than 45). The current recruitment status is unclear.

Study design
This interventional study plans to enroll 180 participants. Participants will be randomly assigned to either the iPREP-RRT intervention or enhanced usual care.
What's involved
You would participate in a 12-week program that includes hospital-based and community-based education, phone calls, and personalized text messaging. Your knowledge about kidney disease and blood pressure will be measured at baseline, one day after a brief intervention, and at weeks 4, 12, and 16.
Compensation
Not stated in the trial record.
Follow-up
Your knowledge will be assessed up to 16 weeks after the start of the intervention.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06397456

Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy

Recruiting
NAAges 18–70InterventionalHealth services
University of Chicago
~180 participants
Updated 2025-11-14 on ClinicalTrials.gov
What's tested:In-Person Patient EducationCommitment to ChangeBlood pressure monitoringWritten Patient EducationText-based reinforcement for CKD self-managementCommunity-based education session, reinforcement for self-management

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Kidney Disease Knowledge Questionnaire (KIKS)
Measured over Baseline, 1 day Post Brief Intervention, Week 4, Week 12, Week 16
+3 more outcomes measured
Chronic Kidney Disease
Hypertension

NCT06397456

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Chicago Medical Center

    Chicago, Illinoisstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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Eligibility criteria

Inclusion

Patients over the age of 18 and under 70
Admitted to the University of Chicago inpatient general medicine service
Likely hospital stay greater than 48 hours
Diagnosis of advanced CKD (Stage 3B or above, as determine by problem list, ICD- 10 codes or eGFR\<45 during admission and from previous medical encounters)
Self-identify as Black or African American

Exclusion

Non-English speaking
Unable to communicate due to current medical status
Unable to consent due to mental status
Expected hospital stay less than 24 hour
Current admission in ICU
  • Kidney Disease Knowledge Questionnaire (KIKS)Baseline, 1 day Post Brief Intervention, Week 4, Week 12, Week 16

    The Kidney Disease Knowledge Questionnaire (KIKS) is a validated instrument that assesses CKD knowledge. Scores range from 0 (no knowledge)-28 (full knowledge). Change =Post intervention-Baseline scores, and Follow-up (Week 4, Week 12, Week 16)-Baseline

  • ESRD KnowledgeBaseline, 1 day Post Brief Intervention, Week 4, Week 12, Week 16

    The Kidney Failure Treatment Knowledge is an investigator developed tool that assesses knowledge of 6 ESKD treatment options using a Likert scale (0=no knowledge and 4=a great deal of knowledge). Possible scores range from 0-24. Change =Post intervention-Baseline scores, and Follow-up (Week 4, Week 12, Week 16)-Baseline

  • Blood Pressure KnowledgeBaseline, 1 day Post Brief Intervention, Week 4, Week 12, Week 16

    Blood Pressure Knowledge Scale (BPKS, revised) is an 11-item scale; a summed score is computed. Scores range from 7 to 77 and higher scores indicate greater knowledge. Change =Post intervention-Baseline scores, and Follow-up (Week 4, Week 12, Week 16)-Baseline

  • CKD Self-ManagementBaseline, Week 8, Week 12, Week 16

    The CKD Self-Management Knowledge Toolkit (CKD-SMKT) is a validated 10 item survey to assess participants CKD self-management behaviors. The survey consists of 2 true /false questions for each of the 10 self-care domains and can be scored from 0 (no self-care) to 20 (full self-care). Change is Follow-up Score (Week 8, Week 12, Week 16)-Baseline