This study aims to better understand why some people with Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD) experience worsening lung problems. Researchers will collect information from 450 participants with RA-ILD, including blood samples, cheek swabs, and questionnaires. They will also look at results from standard medical tests like HRCT scans (detailed lung X-rays), pulmonary function tests (breathing tests), and 6-minute walk tests. The goal is to find specific patterns in imaging and blood markers that predict who is at highest risk for their RA-ILD getting worse over five years. You can join if you are 18 to 90 years old, have a diagnosis of RA-ILD, and have not received specific medication for RA-ILD.

Study design

This is an observational study involving 450 participants with RA-ILD. It is not testing a new treatment, but rather collecting information to understand the disease better.

What's involved

You would provide blood samples, buccal (cheek) swabs, and complete questionnaires at the start, and then blood samples and questionnaires every four months. You would also have standard medical tests like lung function tests and HRCT scans at baseline, year 1, and year 2 if performed clinically.

Compensation

Not stated in the trial record.

Follow-up

The study aims to evaluate changes over a 5-year period, with follow-up visits for blood samples and questionnaires every four months, and additional tests at year 1 and year 2.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.