Research on Lung Transplant Outcomes
This study is collecting information from 2,600 lung transplant candidates, donors, and recipients to better understand lung transplant outcomes. Researchers will gather detailed medical information, blood samples, and patient-reported outcomes (how you feel and function) to create a valuable resource. The goal is to learn how different donor and medical practices affect transplant success and to find markers in the blood that can predict complications like infection or rejection. You can join if you are 18 or older and are either waiting for a lung transplant or had one within the last 30 days. The study will measure how many people join, how complete the information collected is, and how many samples and patient-reported outcomes are gathered over three years.
- Study design
- This is an observational study involving 2,600 participants, including lung transplant donors, candidates, and recipients. It will follow standard medical practices at each center.
- What's involved
- You will have data collected and blood samples taken at the same time as your routine medical visits. This includes collecting plasma, serum, and DNA samples.
- Compensation
- Not stated in the trial record.
- Follow-up
- The study will track certain outcomes for up to 3 years after enrollment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes
At a glance
Conditions
Where it's being run
19 sites across 15 statesStudy leadership
- Scott M Palmer, MD, MHS · PRINCIPAL_INVESTIGATOR · Duke University School of Medicine, Department of Medicine
- Jason D Christie, MD, MSCE · PRINCIPAL_INVESTIGATOR · University of Pennsylvania
- Megan L Neely, PhD · PRINCIPAL_INVESTIGATOR · Duke University School of Medicine, Department of Biostatistics and Bioinformatics
Who to contact
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What this trial measures
- Number of participants enrolled and critical variable completeness3 years
To collect detailed clinical data, blood samples (including DNA), and PROs in 2,600 lung transplant candidates, donors, and recipients across the participating LTC centers to create a robust resource that will support a broad range of additional future clinical and translational research objectives
- Number of PROs collected per patient3 years
To collect clinical data and PROs that will specifically support future research studies to determine how variation in donor, surgical, or medical management practices across the participating LTC centers are associated with specific differences in relevant clinical outcomes such as PGD, AR, AMR, ALAD, post-transplant infections, PROs including health-related quality of life, or one-year survival.
- Number of specimens per participant collected3 years
To collect clinical data and biosamples that will specifically support future research studies to identify serum biomarkers that are associated with or predict the development of PGD, AR, AMR, ALAD, or CLAD.