RECHARGE Trial: Comparing Heart Procedures for Women with Coronary Artery Disease
This research study, called RECHARGE: Women, is for women with coronary artery disease (CAD), a condition where the arteries supplying blood to the heart become narrowed or blocked. The study compares two procedures to improve blood flow: coronary artery bypass grafting (CABG), which is open-heart surgery, and percutaneous coronary intervention (PCI), a non-surgical procedure using a balloon and stent. Researchers want to see which procedure leads to better survival and quality of life over five years. You may be able to join if you are a woman at least 18 years old with CAD that your doctors believe could be treated by either CABG or PCI. The study is currently recruiting 600 participants.
- Study design
- This is a randomized study where 600 participants will be assigned to receive either CABG or PCI. It is an open-label study, meaning both you and your doctors will know which treatment you receive.
- What's involved
- You will have follow-up phone calls at specific times for the first three years, and then yearly for up to ten years. You will also have a repeat echocardiogram and blood test at one year.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for 5 to 10 years after their procedure to track their health and quality of life.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Women
At a glance
Conditions
Where it's being run
18 sites across 11 statesStudy leadership
- Mario Gaudino, MD, PhD, MSCE, FEBCTS, FACC · PRINCIPAL_INVESTIGATOR · Weill Medical College of Cornell University
- Gregg S Stone, MD, FACC, MSCAI · PRINCIPAL_INVESTIGATOR · Icahn School of Medicine at Mount Sinai
Who to contact
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What this trial measures
- Hierarchical composite of all-cause death and time-averaged change from baseline in generic quality of life using the SF-12v25 years
Generic quality of life (QOL) will be assessed by utilizing the 12-item Short Form Survey (SF-12v2). The score ranges from 1-100, with higher scores indicating a better health status. The win ratio method will be utilized