This study is testing if Fisetin, a natural substance found in fruits like strawberries, can help people with Peripheral Arterial Disease (PAD). PAD is a condition where narrowed arteries reduce blood flow to your limbs, often causing leg pain when walking (claudication). Fisetin is thought to work by getting rid of 'senescent cells,' which are old, damaged cells that can contribute to aging and disease. Researchers want to see if Fisetin can reduce these cells and improve how far you can walk in six minutes. You could be eligible if you are 50 or older and have PAD, confirmed by specific blood pressure measurements in your ankles. The study aims to enroll 34 participants.

Study design

This is a pilot randomized trial, meaning participants will be randomly assigned to receive either Fisetin or a placebo (an inactive substance). The study plans to enroll 34 participants.

What's involved

Participants will be followed for four months. Your walking distance will be measured at the start and again at the end of the study.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for four months after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.