Clevidipine for High Blood Pressure After Intracerebral Hemorrhage
This study is looking at how well two different medications, Clevidipine Injection and other standard intravenous (IV) blood pressure medicines (like nicardipine), work to lower high blood pressure in people who have had an intracerebral hemorrhage (a type of stroke caused by bleeding in the brain). Researchers want to see if Clevidipine Injection helps more people reach a stable blood pressure target within 60 minutes compared to the other IV medicines. You might be able to join if you are 18 to 99 years old, have new stroke symptoms within 12 hours, and can start one of these IV treatments within 12 hours of your symptoms starting. The study aims to enroll 1018 participants.
- Study design
- This is an observational study, meaning researchers will watch how patients are treated with either Clevidipine or other standard IV blood pressure medicines. It plans to include 1018 participants.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Blood pressure will be monitored at 15 minutes after treatment begins.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage
At a glance
Conditions
Where it's being run
20 sites across 11 statesWho to contact
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What this trial measures
- Blood Pressure Monitoring15 minutes
To compare the rate of hypertensive subjects with ICH who reach SBP target with stability within 60 minutes of enrollment, among patients treated with IV clevidipine with those treated with alternate IV antihypertensive regimen. SBP target with stability is defined as achieving a SBP of less than 150 mm Hg and greater than 130 mm Hg with two subsequent consecutive recordings at least 15 minutes apart that show SBP of less than 150 mm Hg and greater than 130 mm Hg.