Clevidipine for High Blood Pressure After Intracerebral Hemorrhage

This study is looking at how well two different medications, Clevidipine Injection and other standard intravenous (IV) blood pressure medicines (like nicardipine), work to lower high blood pressure in people who have had an intracerebral hemorrhage (a type of stroke caused by bleeding in the brain). Researchers want to see if Clevidipine Injection helps more people reach a stable blood pressure target within 60 minutes compared to the other IV medicines. You might be able to join if you are 18 to 99 years old, have new stroke symptoms within 12 hours, and can start one of these IV treatments within 12 hours of your symptoms starting. The study aims to enroll 1018 participants.

Study design
This is an observational study, meaning researchers will watch how patients are treated with either Clevidipine or other standard IV blood pressure medicines. It plans to include 1018 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Blood pressure will be monitored at 15 minutes after treatment begins.

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NCT06402968

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

Recruiting
Not specifiedAges 18+Observational
Zeenat Qureshi Stroke Institute
~1,018 participants
Updated 2026-08-07 on ClinicalTrials.gov
What's tested:Clevidipine InjectionAlternate IV Antihypertensive Regimen

At a glance

Recruiting sites
20 of 20 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Blood Pressure Monitoring
Measured over 15 minutes
Intracerebral Hemorrhage
Stroke
Hypertension
20 sites across 11 states
California3
Florida3
Ohio3
Georgia2
New York2
Texas2
Indiana1
Maryland1

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  • Blood Pressure Monitoring15 minutes

    To compare the rate of hypertensive subjects with ICH who reach SBP target with stability within 60 minutes of enrollment, among patients treated with IV clevidipine with those treated with alternate IV antihypertensive regimen. SBP target with stability is defined as achieving a SBP of less than 150 mm Hg and greater than 130 mm Hg with two subsequent consecutive recordings at least 15 minutes apart that show SBP of less than 150 mm Hg and greater than 130 mm Hg.