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Understanding Sentence Production in Aphasia

This study is looking for 350 people, including those with aphasia (language problems after a stroke) and healthy adults, to understand how the brain produces sentences. Researchers will ask participants to speak and understand words and sentences with different changes, like how words are formed or their meaning. The goal is to better understand how language works in the brain and how it breaks down in people with aphasia after a stroke. This knowledge could help develop better treatments in the future. We will measure accuracy, response time, and brain activity over about one year. You must be at least 18 years old and a native English speaker to participate. The study status is currently unclear.

Study design
This is an interventional study planning to enroll 350 participants. It includes people with aphasia due to stroke and healthy adults (younger or older).
What's involved
Participants will be asked to speak and understand words and sentences with different linguistic manipulations. The study will last for an average of one year.
Compensation
Not stated in the trial record.
Follow-up
Measurements for accuracy, response time, and brain activity will be taken through the completion of the study, an average of one year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06405594

Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

Recruiting
NAAges 18+Interventional
University of Maryland, College Park
~350 participants
Updated 2024-09-03 on ClinicalTrials.gov
What's tested:Language Condition

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Accuracy
Measured over through the completion of the study, an average of 1 year
+2 more outcomes measured

Conditions

Aphasia, Acquired
Stroke
Healthy Aging

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AphasiaStroke

NCT06405594

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Maryland

    College Park, Marylandstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Yasmeen Faroqi-Shah, PhD · PRINCIPAL_INVESTIGATOR · University of Maryland

Who to contact

Yasmeen Faroqi-Shah, PhD
[email protected]
3014054229
Email the study team

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Eligibility criteria

Inclusion

At least 18 years of age
Persons with acquired aphasia are defined as those with a language impairment following left hemisphere brain injury (most likely a stroke).
Neurotypical adults need to be either young (ages 18-30 years) or older (\> 60 years)
Native (or primary) speakers of English

Exclusion

Prior neurological or psychiatric diagnoses or developmental disabilities before the onset of aphasia
do not speak English fluently

What this trial measures

  • Accuracythrough the completion of the study, an average of 1 year

    Response accuracy for each experimental condition will be measured

  • Response timethrough the completion of the study, an average of 1 year

    Response times for each experimental condition will be measured

  • Brain activitythrough the completion of the study, an average of 1 year

    Patterns of brain activity (using magnetoencephalography and MRI) will be measured for each experimental condition